588-64-7Relevant articles and documents
Dual-parameter correlations on rate of dehydration step of a condensation reaction in aqueous solutions of ethanol, propan-2-ol and 2-methylpropan-2-ol
Habibi Yangjeh,Gholami,Mostaghim
, p. 884 - 889 (2001)
The reaction kinetics of the dehydration step of the condensation reaction between phenylhydrazine and benzaldehyde was studied spectrophotometrically in aqueous solutions of ethanol, propan-2-ol and 2-methylpropan-2-ol at pH 11.5 at 25 °C. The apparent second-order rate constants k2app of the reaction increase with mole fraction of water in all the aqueous solutions. Single-parameter correlations of log k2app versus π* (dipolarity/polarizability), α (hydrogen-bond donor acidity) and ETN (normalized polarity parameter) were obtained in all the aqueous solutions. In all cases, the correlations versus ETN and π* are acceptable, but correlations versus α are poor (e.g. in aqueous solutions of ethanol the correlation coefficients are 0.964, 0.967, and 0.751 respectively). The results of dual-parameter correlations of log k2app versus π* and α in all cases represent improvements with regard to the single-parameter models (in aqueous solutions of ethanol r = 0.995; s.e. = 0.038; n = 13). The apparent second-order rate constants of the reaction increase with α, π* and ETN. Increasing the hydrogen-bond donor acidity of the solvent stabilizes the activated complex of the reaction via hydrogen-bond formation with the intermediate. A dual-parameter equation of log k2app versus π* and α was obtained for the combined data set of aqueous solutions (n = 35, r = 0.989, s.e. = 0.062, F2.32 = 719.21), in which π* has the major effect on the reaction rate relative to α. Copyright
Synthesis of 1,1′-([1,1′-Biphenyl]-4,4′-diyl)bis(3-aryl-5-phenylformazans) and 1,1′-([1,1′-Biphenyl]-4,4′-diyl)bis(3-aryl-5-phenyl-5,6-dihydro-1,2,4,5-tetrazin-1-ium) Perchlorates
Alalwan, D. H. K.,Jassim, T.,Kostryukov, S. G.,Kozlov, A. Sh.,Masterova, Yu. Yu.,Tezikova, V. S.
, p. 1600 - 1607 (2021/12/13)
Abstract: New bis-formazans and bis(5,6-dihydro-1,2,4,5-tetrazin-1-ium) perchlorates were synthesized with high yields under mild conditions. 1,1′-([1,1′-Biphenyl]-4,4′-diyl)bis(3-aryl-5-phenylformazans) were obtained by diazo coupling of para-substituted benzaldehyde phenylhydrazones with [1,1′-biphenyl]-4,4′-bis(diazonium chloride). Treatment of the obtained bis-formazans with formaldehyde in the presence of perchloric acid in dioxane afforded 1,1′-([1,1′-biphenyl]-4,4′-diyl)bis(3-aryl-5-phenyl-5,6-dihydro-1,2,4,5-tetrazin-1-ium) diper-chlorates. The structure of the synthesized compounds was confirmed by elemental analyses and UV, IR, and 1H and 13C NMR spectra.
METHODS OF FORMING IMINES, IMINE-RELATED AND IMINE-DERIVED COMPOUNDS USING GREEN SOLVENTS
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Paragraph 0186-0189, (2021/10/22)
The present disclosure relates to using green solvents to synthesize an array of imines, imine-related and imine-derived compounds in an efficient and eco-friendly matter, satisfying green chemistry requirements. Reaction embodiments are performed using solvents, such as ethyl lactate and dimethyl isosorbide, which are both individually characterized as green. In embodiments, solvents include lactic whey and/or water as co-solvents. In these green solvents, the synthesis process discussed herein can produce up to quantitative yields of product at room temperature in a short duration. Embodiments include a method of forming an imine, imine-related or imine-derived compound product. In embodiments, the methods include mixing an aldehyde reactant with a nucleophilic/nitrogen-containing reactant in a green solvent at a temperature between negative twenty degrees Celsius (?20° C.) and positive fifty degrees Celsius (50° C.); stirring the mixture; and forming an imine, imine-related or imine-derived compound product.