58942-31-7

Basic information

• Product Name: 1-methoxy-4-(2-methylcyclopropyl)benzene
• Synonyms: 1-methoxy-4-(2-methylcyclopropyl)benzene
• CAS NO: 58942-31-7
• Molecular Weight: 162.232
• Mol File: 58942-31-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-methoxy-4-(2-methylcyclopropyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methoxy-4-(2-methylcyclopropyl)benzene(58942-31-7)
• EPA Substance Registry System: 1-methoxy-4-(2-methylcyclopropyl)benzene(58942-31-7)

Safety Data

• Hazardous Substances Data: 58942-31-7(Hazardous Substances Data)

Upstream product

• 75-11-6 diiodomethane 
• 104-46-1 anethole 
• 186581-53-3 diazomethane 
• 4180-23-8 E-1-(4'-methoxyphenyl)prop-1-ene 
• 123-11-5 4-methoxy-benzaldehyde 
• 25679-28-1 cis-Anethole 
• 117024-23-4 (η(5)-C5H5)(CO)2Fe-CH(OMe)(p-OCH3Ph) 
• 114095-59-9 (1S*, 2S*)-2-((4-methoxyphenyl)cyclopropyl)methanol 
• 75-09-2 dichloromethane 
• 243665-13-6 (2E)-N-methoxy-3-(4-methoxyphenyl)-N-methylprop-2-enamide 
• 110826-20-5 (±)-trans-2-(4-methoxyphenyl)cyclopropanecarboxylic acid 

Downstream Products

• 142746-00-7 3-methyl-5-(4-methoxyphenyl)-2-isoxazoline 
• 142746-12-1 4-methyl-5-(4-methoxyphenyl)-2-isoxazoline 

Relevant articles and documents

Nickel Nanoparticle Catalyzed Mono- and Di-Reductions of gem-Dibromocyclopropanes Under Mild, Aqueous Micellar Conditions

Mild mono- and di-hydrodehalogenative reductions of gem-dibromocyclopropanes are described, providing an easy and green approach towards the synthesis of cyclopropanes. The methodology utilizes 0.5–5 mol % TMPhen-nickel as the catalyst, which, when activated with a hydride source such as sodium borohydride, cleanly and selectively dehalogenates dibromocyclopropanes. Double reduction proceeds in a single operation at temperatures between 20–45 °C and at atmospheric pressure in an aqueous designer surfactant medium. At lower loading and either in the absence of ligand or in the presence of 2,2′-bipyridine, this new technology can also be used to gain access to not only monobrominated cyclopropanes, interesting building blocks for further use in synthesis, but also mono- or di-deuterated analogues. Taken together, this base-metal-catalyzed process provides access to cyclopropyl-containing products and is achieved under environmentally responsible conditions.

A Stereoconvergent Cyclopropanation Reaction of Styrenes

The first stereoconvergent cyclopropanation reaction by means of photoredox catalysis using diiodomethane as the methylene source is described. This transformation exhibits broad functional group tolerance and it is characterized by an excellent stereocontrol en route to trans-cyclopropanes regardless of whether E- or Z-styrene substrates were utilized.

Highly diastereoselective hydrostannylation of allyl and homoallyl alcohols with dibutyl(trifluoromethanesulfoxy)stannane

Dibutyl(trifluoromethanesulfoxy)stannane (Bu2Sn(OTf)H, 1a) was found to be very valuable for highly diastereoselective homolytic hydrostannylation of allyl and homoallyl alcohols. α,β-Disubstituted allyl alcohols and α,γ-disubstituted homoallyl alcohols were converted into γ- and δ-stannylated alcohols with high 1,2-syn and 1,3-syn diastereoselectivity, respectively. The origin of the stereochemical outcomes can be rationalized by conformational fixation of the intermediary β-stannylalkyl radical by coordination of the hydroxy group to the Lewis acidic tin center. Copyright