590-97-6Relevant articles and documents
Acetic acid esters of (bromomethyl) preparation method (by machine translation)
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Paragraph 0013; 0014; 0015, (2016/10/27)
The invention discloses a acetic acid (bromomethyl) method for preparing ester, under room temperature, is added to the zinc chloride in methylene dichloride solution of acetyl bromide, by adding paraformaldehyde under ice bath, the reaction at room temperature overnight, filtering, multiple vacuum distillation, collecting oil bath temperature is 130 °C, steam temperature is 70-80 °C fraction, get colorless liquid acetic acid (bromomethyl) ester. This invention adopts the zinc chloride, acetyl bromide, raw materials such as poly-formaldehyde having a complicated structure to synthesize the compound acetic acid (bromomethyl) ester, the product yield of up to 45%, and the crystal effect is good, high purity, as a follow-up chemical and biological experiment provide a high-purity sample or sample. (by machine translation)
Nitroxyl compounds and drugs and reagents containing the same as the active ingredient
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, (2008/06/13)
Nitroxyl compounds represented by general formula (I) which are usable in acquiring information about active oxygen or in vivo free radicals as biological images such as magnetic resonance images or magnetoencephalograms, wherein A represents hydrogen or —L—(CH2)n—OCOR (wherein L represents —COO— or -alkylene-COO—; and R represents C1-4alkyl); R1, R2, R3, and R4represent each C1-4alkyl; and n is a number of from 1 to 4. Drugs and reagents containing the above compounds are usable in preventing, treating or diagnosing ischemic diseases, digestive diseases, cancer, cranial nervous diseases accompanied by nerve degeneration, inflammation, cataracts, or drug-induced organopathy.
Synthesis of α-Haloalkyl Esters from α-Arylthioalkyl Esters
Benneche, Tore,Strande, Per,Wiggen, Unni
, p. 74 - 77 (2007/10/02)
α-Monohaloalkyl esters have been prepared under mild conditions in high yields by selective cleavage of the carbon-sulfur bond in α-phenylthioalkyl esters using sulfuryl chloride or bromine.The intermediate α-phenylthioalkyl esters have been prepared by alkylation of the corresponding carboxylic acids with readily accessible α-haloalkyl phenyl sulphides.
