59280-70-5

Basic information

• Product Name: 4'-CHLORO-2'-FLUOROACETANILIDE
• Synonyms: N-(4-CHLORO-2-FLUOROPHENYL)ACETAMIDE;TIMTEC-BB SBB003684;2'-FLUORO-4'-CHLOROACETANILIDE;4'-CHLORO-2'-FLUOROACETANILIDE;4-CHLORO-2-FLUOROACETANILIDE;4'-Chloro-2'-fluoroacetanilide 98%;4'-Chloro-2'-fluoroacetanilide98%;4'-CHLORO-2'-FLUOROACETANILIDE , 99+%
• CAS NO: 59280-70-5
• Molecular Formula: C₈H₇ClFNO
• Molecular Weight: 187.6
• EINECS: -0
• Product Categories: Anilines, Amides & Amines;Chlorine Compounds;Fluorine Compounds
• Mol File: 59280-70-5.mol
• Article Data: 29

Chemical Properties

• Melting Point: 154-156 °C(lit.)
• Boiling Point: 312.8 °C at 760 mmHg
• Flash Point: 143 °C
• Appearance: pink to light brown crystalline powder
• Density: 1.3020 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.16±0.70(Predicted)
• BRN: 2092371
• CAS DataBase Reference: 4'-CHLORO-2'-FLUOROACETANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-CHLORO-2'-FLUOROACETANILIDE(59280-70-5)
• EPA Substance Registry System: 4'-CHLORO-2'-FLUOROACETANILIDE(59280-70-5)

Safety Data

• Hazard Codes: T,Xi
• Statements: 23/24/25-36/37/38
• Safety Statements: 45-36/37/39-36-26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 59280-70-5(Hazardous Substances Data)

Upstream product

• 57946-56-2 2-fluoro-4-chloroaniline 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 399-31-5 N-(2-fluorophenyl)acetamide 

Downstream Products

• 95635-45-3 N-(4-chloro-2-fluoro-5-nitrophenyl)acetamide 
• 61330-03-8 2-(4-chloro-2-fluorophenyl)-3a,4,5,6,7,7a-hexahydro-1H-isoindole-1,3(2H)-dione 
• 61714-44-1 2-(4-chloro-2-fluorophenylaminocarbonyl)-1-cyclohexene-1-carboxylic acid 
• 1442470-80-5 N-(4-chloro-2-fluoro-3-(hydroxymethyl)phenyl)acetamide 
• 1442470-82-7 3-acetamido-6-chloro-2-fluorobenzyl methanesulfonate 
• 1442470-84-9 N-(4-chloro-3-(cyanomethyl)-2-fluorophenyl)acetamide 
• 1379666-58-6 (E)-3-(3-acetamido-6-chloro-2-fluorophenyl)acrylic acid 
• 1379666-59-7 3-(3-acetamido-2-fluorophenyl)propanoic acid 
• 1379666-61-1 5-(benzylamino)-4-fluoro-2,3-dihydro-1H-inden-1-one 
• 1379666-62-2 2-(benzyl(4-fluoro-1-oxo-2,3-dihydro-1H-inden-5-yl)amino)-N,N-diethylacetamide 
• 1000590-86-2 N-(4-chloro-2-fluoro-3-iodophenyl)acetamide 
• 50739-39-4 2-(bromomethyl)-6-chloro-1,3-benzothiazole 
• 1379666-56-4 N-(4-chloro-2-fluoro-3-formylphenyl)acetamide 
• 1442472-19-6 1-(4-chloro-3-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-3-phenylurea 

Relevant articles and documents

HETEROCYCLIC COMPOUND

Provided is a heterocyclic compound that may have a GCN2 inhibitory action, and is expected to be useful for the prophylaxis or treatment of GCN2 associated diseases including cancer and the like. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.

CYCLOPENTYLBENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PSYCHOTIC AND COGNITIVE DISORDERS

The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein n, L, X, Ra, Rb, R1, R2 and R3 their preparation, pharmaceutical compositions containing them and their use in therapy.

COMPOUND, KINESIN SPINDLE PROTEIN INHIBITOR, AND APPLICATION THEREOF

A compound represented by the following General Formula (I): where, in General Formula (I), R1 and R2 each represent an alkyl group which may have a substituent, R3 represents the following General Formula (II) or (III), and R1 and R2 may be identical or different, where, in General Formulas (II) and (III), X represents a hydrogen atom or a halogen atom, R4 represents a methyl group, a dimethyl group or an oxygen atom, and * represents a binding position.