59777-72-9

Basic information

• Product Name: Ethyl 2-sulfamoylbenzoate
• Synonyms: O-CARBOETHOXYBENZENE SULFONAMIDE;2-SULFONAMIDOBENZOIC ACID ETHYL ESTER;2-SULFAMOYLBENZOIC ACID ETHYL ESTER;2-Ethylcarbonylbenzene sulfonamide;2-CARBOETHOXYBENZENE SULFONAMIDE;2-(AMINOSULFONYL)BENZOIC ACID ETHYL ESTER;ETHYL 2-SULFAMOYLBENZOATE;ETHYL 2-SULFONAMIDOBENZOATE
• CAS NO: 59777-72-9
• Molecular Formula: C₉H₁₁NO₄S
• Molecular Weight: 229.25
• Product Categories: pharmacetical
• Mol File: 59777-72-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 83 °C
• Boiling Point: 408.283 °C at 760 mmHg
• Flash Point: 200.723 °C
• Appearance: /
• Density: 1.327 g/cm³
• Vapor Pressure: 7.08E-07mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 9.67±0.60(Predicted)
• CAS DataBase Reference: Ethyl 2-sulfamoylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-sulfamoylbenzoate(59777-72-9)
• EPA Substance Registry System: Ethyl 2-sulfamoylbenzoate(59777-72-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 59777-72-9(Hazardous Substances Data)

Usage

General Description

Ethyl 2-sulfamoylbenzoate is a chemical compound with the molecular formula C9H11NO4S. This chemical substance appears as a white crystalline powder and is classified as benzoic acid or a derivative thereof. It possesses the properties of an aromatic sulfonamide and an alkyl sulfate. It is soluble in ethanol, chloroform, and dilute alkali solution. The chemical is primarily used in biochemical research and pharmaceutical applications. However, specific health and safety information about this compound is limited and handling should always be carried out by trained professionals adhering to safety guidelines.

InChI:InChI=1/C9H11NO4S/c1-2-14-9(11)7-5-3-4-6-8(7)15(10,12)13/h3-6H,2H2,1H3,(H2,10,12,13)

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 3306-62-5 2-AMINOBENZENESULFONAMIDE 
• 88-19-7 methyl 2-(aminosulfonyl)benzoate 
• 90982-32-4 chlorimuron ethyl 
• 81-07-2 saccharin 
• 64-17-5 ethanol 
• 632-24-6 2-sulfamoyl-benzoic acid 
• 75-03-6 ethyl iodide 
• 103008-54-4 ethyl 2–(chlorosulfonyl)benzoate 

Downstream Products

• 165395-27-7 C₁₁H₁₃NO₆S 
• 1569309-92-7 2-[4-(1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)butylsulfamoyl]benzoic acid 
• 77375-79-2 o-Ethoxycarbonylbenzenesulfonyl isocyanate 
• 1416567-33-3 C₁₅H₁₅BrN₄O₆S 
• 100594-02-3 C₁₅H₁₅IN₄O₆S 
• 936-16-3 2,3-dihydro-1,2-benzisothiazole 1,1-dioxide 
• 65270-84-0 2-(hydroxymethyl)benzenesulfonamide 
• 1373318-58-1 2-(ethoxymethyl)benzenesulfonamide 
• 3416-59-9 N-benzylsaccharin 
• 7499-96-9 2-n-butyl-1,1-dioxo-1,2-dihydro-1λ6-benzo[d]isothiazo-3-one 
• 81-07-2 saccharin 
• 1256107-53-5 2-(ethoxycarbonyl)benzenesulfanenitrile 
• 64-17-5 ethanol 

Relevant articles and documents

Syntheses, biological activities and SAR studies of novel carboxamide compounds containing piperazine and arylsulfonyl moieties

A series of novel carboxamide compounds 19a-19j, 20a-20j and 22a-22d containing piperazine and arylsulfonyl moieties have been synthesized. The bioassay results showed that some compounds exhibited favorable herbicidal activities against dicotyledonous plants and many of them possessed excellent antifungal activities. Among 24 novel compounds, some showed superiority over the commercial fungicides Chlorothalonil, Dimethomorph, Thiophanate-methyl, Iprodione, and Zhongshengmycin at 500 mg/L concentration. Some compounds also exhibited high KARI inhibitory activity at 100 γ1/4g/mL concentration and could be used as new KARI lead inhibitors for further studies. Moreover, SAR of these new compounds were comprehensively investigated using different computational methods in which 3D-QSAR model obtained provided useful information for further structural optimization for the discovery of new fungicides. The results of this research will contribute to explore comprehensive biological activities of piperazine-containing compounds in different areas of chemistry.

Sulfonylureas as dual acting agents - Synthesis and biological activity

2-Amino-5-aryl/alkyl-1,3,4-thiadiazoles 3a-e were used as intermediates in the synthesis of some 1,3-substituted urea derivatives 5a-o to evaluate their antidiabetic activity as well as antibacterial activity. The obtained compounds exhibited marginal activity against the animal models and the selected microorganisms.

Herbicidal compounds, their production and use

A compound of the general formula STR1 wherein R1 is a phenyl group which may be substituted, R2 and R3 respectively are a lower alkyl or lower alkoxy group, Z is CH or N and n is 0 or 1, or a salt thereof which is useful as a herbicide.