5989-81-1 Usage
Chemical Properties
Different sources of media describe the Chemical Properties of 5989-81-1 differently. You can refer to the following data:
1. White powder
2. Lactose occurs as white to off-white crystalline particles or powder.
It is odorless and slightly sweet-tasting. Spray-dried directcompression
grades of lactose are generally composed of 80–90%
specially prepared pure a-lactose monohydrate along with 10–20%
of amorphous lactose.
Uses
alpha-D-Lactose monohydrate is used as a carrier and stabiliser of aromas, pharmaceutical products, Food industry.
Production Methods
A suspension of a-lactose monohydrate crystals in a lactose solution
is atomized and dried in a spray drier. Approximately 10–20%
of the total amount of lactose is in solution and the remaining
80–90% is present in the crystalline form. The spray-drying process
predominantly produces spherical particles. The compactibility of
the material and its flow characteristics are a function of the
primary particle size of the lactose monohydrate and the amount of
amorphous lactose.
Definition
A sugar that occurs in many
plants. It is extracted commercially from sugar cane and sugar beet. Sucrose is a disaccharide formed from a glucose unit and
a fructose unit. It is hydrolyzed to a mixture of fructose and glucose by the enzyme
invertase. Since this mixture has a different
optical rotation (levorotatory) than the
original sucrose, the mixture is called invert sugar.
Pharmaceutical Applications
Spray-dried lactose is widely used as a binder, filler-binder, and flow
aid in direct compression tableting.
Biochem/physiol Actions
alpha-Lactose is the primary sugar present in milk and the main energy source to a newborn mammalian through its mother′s milk. It is digested by the intestinal lactase (EC 3.2.1.108), an enzyme expressed in newborns. The enzyme′s activity declines following weaning which can lead to lactose intolerance in adult mammals.
Safety
Lactose is widely used in pharmaceutical formulations as a diluent
in oral capsule and tablet formulations. It may also be used in
intravenous injections.
Adverse reactions to lactose are largely due to lactose intolerance,
which occurs in individuals with a deficiency of the enzyme
lactase.
storage
Spray-dried lactose should be stored in a well-closed container in a
cool, dry place.
Incompatibilities
Lactose is a reducing sugar. The amorphous lactose, which is the
most reactive form of lactose present in spray-dried lactose, will
interact more readily than conventional crystalline grades.
Typical reactions include the Maillard reaction with either
primary or secondary amines.
Check Digit Verification of cas no
The CAS Registry Mumber 5989-81-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,8 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5989-81:
(6*5)+(5*9)+(4*8)+(3*9)+(2*8)+(1*1)=151
151 % 10 = 1
So 5989-81-1 is a valid CAS Registry Number.
InChI:InChI: 1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2
