60-38-8

Basic information

• Product Name: 3-ACETYL STROPHANTHIDIN
• Synonyms: 19-oxo-3-beta,5,14-trihydroxy-5-beta-card-20(22)-enolid3-acetate;acetyl-k-strophanthidine;acetylstrophanthidine;erysimupicroneacetate;strophanthidin3-acetate;3-ACETYL STROPHANTHIDIN;ACETYL-STROPHANTHIDIN;ACETYL-STROPHANTHIDIN, 3-
• CAS NO: 60-38-8
• Molecular Formula: C₂₅H₃₄O₇
• Molecular Weight: 446.53
• EINECS: 200-474-0
• Mol File: 60-38-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 246-248℃
• Boiling Point: 612.8 °C at 760 mmHg
• Flash Point: 205.7 °C
• Appearance: /
• Density: 1.31±0.1 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: −20°C
• CAS DataBase Reference: 3-ACETYL STROPHANTHIDIN(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ACETYL STROPHANTHIDIN(60-38-8)
• EPA Substance Registry System: 3-ACETYL STROPHANTHIDIN(60-38-8)

Safety Data

• Hazard Codes: T+
• Statements: 26/27/28
• Safety Statements: 22-36/37/39-45
• RIDADR: UN 2811 6.1/PG 1
• WGK Germany: 3
• RTECS: FH5311400
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 60-38-8(Hazardous Substances Data)

Usage

Uses

Acetylstrophanthidin is a cardiac glycoside with biphasic effect.

Definition

ChEBI: An acetate ester that is strophanidin acetylated at the 3beta-hydroxy group.

Upstream product

• 125139-81-3 C₂₉H₄₂BrO₉P 
• 125139-84-6 Acetic acid (3S,8R,9S,10S,13R,17S)-10-formyloxymethyl-13-methyl-17-(5-oxo-2,5-dihydro-furan-3-yl)-2,3,4,7,8,9,10,11,12,13,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 
• 125139-86-8 Acetic acid (3S,5S,8R,9S,10R,13R,14S,17R)-10-formyloxymethyl-5,14-dihydroxy-13-methyl-17-(5-oxo-2,5-dihydro-furan-3-yl)-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 
• 125139-79-9 C₂₅H₃₃BrO₆ 
• 125139-82-4 C₂₅H₃₁BrO₅ 
• 125139-83-5 Acetic acid (3S,8R,9S,10S,13R,17S)-10-hydroxymethyl-13-methyl-17-(5-oxo-2,5-dihydro-furan-3-yl)-2,3,4,7,8,9,10,11,12,13,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 
• 125139-80-2 C₂₃H₃₁BrO₅ 
• 125175-45-3 C₂₃H₃₁BrO₄ 
• 67270-87-5 C₂₃H₂₉BrO₄ 
• 125139-78-8 C₂₃H₃₁BrO₄ 
• 125139-77-7 Acetic acid (3S,5R,6R,8S,9S,10R,13S,14S)-17-acetyl-5-bromo-6-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,10,11,12,13,14,15-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 
• 979-02-2 16-dehydropregnenolone acetate 
• 4947-61-9 strophanthidol 3β-acetate 
• 108-24-7 acetic anhydride 

Relevant articles and documents

SYNTHESIS OF STROPHANTHIDIN

A 16-step synthesis of strophanthidin (3) from a commercially available steroid 4 is described.Salient features of this approach are the selective reduction of the dienone system in 7 to give 8 and a one-pot introduction of 5β- and 14β-hydroxyls by addition of HOBr (14 -> 15).The stereo- and regioselectivity of the HOBr addition to the 5,6-double bond is controlled by 19-formyloxy group.