60463-12-9

Basic information

• Product Name: 5-HYDROXY-2-NITROBENZYL ALCOHOL
• Synonyms: 5-HYDROXY-2-NITROBENZYL ALCOHOL;RARECHEM AL BD 0679;2-Nitro-5-hydroxybenzenemethanol;2-Nitro-5-hydroxybenzyl alcohol;3-(Hydroxymethyl)-4-nitrophenol;5-Hydroxy-2-nitrobenzenemethanol;(5-Hydroxy-2-nitrophenyl)methanol;5-Hydroxy-2-nitrobenzyl alcohol 97%
• CAS NO: 60463-12-9
• Molecular Formula: C₇H₇NO₄
• Molecular Weight: 169.13
• Product Categories: Benzhydrols, Benzyl & Special Alcohols;Alcohols;C7 to C8;Oxygen Compounds;Building Blocks;C7 to C8;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 60463-12-9.mol
• Article Data: 11

Chemical Properties

• Melting Point: 111-115 °C(lit.)
• Boiling Point: 398.6°C at 760 mmHg
• Flash Point: 184.1°C
• Appearance: /
• Density: 1.489g/cm³
• Vapor Pressure: 4.54E-07mmHg at 25°C
• Refractive Index: 1.644
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 6.99±0.10(Predicted)
• CAS DataBase Reference: 5-HYDROXY-2-NITROBENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 5-HYDROXY-2-NITROBENZYL ALCOHOL(60463-12-9)
• EPA Substance Registry System: 5-HYDROXY-2-NITROBENZYL ALCOHOL(60463-12-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 60463-12-9(Hazardous Substances Data)

Usage

Description

5-HYDROXY-2-NITROBENZYL ALCOHOL is an organic compound with the molecular formula C7H7NO4. It is characterized by the presence of a hydroxyl group at the 5th position and a nitro group at the 2nd position of the benzyl alcohol structure. 5-HYDROXY-2-NITROBENZYL ALCOHOL is known for its potential applications in various chemical and pharmaceutical processes due to its unique functional groups.

Uses

Used in Chemical Synthesis:
5-HYDROXY-2-NITROBENZYL ALCOHOL is used as a key intermediate in the synthesis of various organic compounds. Its hydroxyl and nitro groups can be further modified or reacted with other molecules to produce a wide range of products.
Used in Pharmaceutical Applications:
5-HYDROXY-2-NITROBENZYL ALCOHOL is used as a starting material for the development of new pharmaceutical compounds. Its unique structure and functional groups can be exploited to design and synthesize novel drugs with potential therapeutic applications.
Used in Polymer Science:
5-HYDROXY-2-NITROBENZYL ALCOHOL is used as a difunctional photo-responsive initiator in the synthesis of thermo-responsive and photo-cleavable amphiphilic block copolymers. These copolymers contain photodegradable linkers as junction points between hydrophilic and hydrophobic chains, which can be utilized in various applications such as drug delivery systems, self-assembling materials, and stimuli-responsive materials.
Used in the Synthesis of 5-(2′-(DIMETHYLAMINO)ETHOXY)-2-NITROBENZYL ALCOHOL:
5-HYDROXY-2-NITROBENZYL ALCOHOL is used as a precursor in the synthesis of 5-(2′-(dimethylamino)ethoxy)-2-nitrobenzyl alcohol. This derivative can be employed in various applications, such as photochemical reactions and the development of new materials with unique properties.

InChI:InChI=1/C7H7NO4/c9-4-5-3-6(10)1-2-7(5)8(11)12/h1-3,9-10H,4H2

Upstream product

• 42454-06-8 2-nitro-5-hydroxybenzaldehyde 

Downstream Products

• 161009-59-2 5-((2-methoxy)ethoxymethoxy)-2-nitrophenylmethanol 
• 68423-36-9 (5-(benzyloxy)-2-nitrophenyl)methanol 
• 403511-55-7 Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-(5-hydroxy-2-nitro-benzyloxy)-tetrahydro-pyran-4-yl ester 
• 872578-78-4 (5-(3-azidopropoxy)-2-nitrophenyl)methanol 
• 177275-28-4 2-nitro-5-(2-quinolylmethoxy)benzyl alcohol 
• 189359-78-2 2-Nitro-5-(2-propyloxy)benzyl alcohol 
• 1379457-35-8 5-propargylether-2-nitrobenzyl carbamate 
• 1379457-36-9 5-propargyl-2-nitrobenzyl carbamate 
• 647843-25-2 (5-ethoxy-2-nitro-phenyl)-methanol 
• 495400-11-8 Acetic acid (2R,3R,4S,5R,6R)-3-acetoxy-6-acetoxymethyl-2-(5-hydroxy-2-nitro-benzyloxy)-5-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-4-yl ester 
• 205369-83-1 (3-Hydroxymethyl-4-nitro-phenoxy)-acetic acid methyl ester 

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