647843-25-2Relevant articles and documents
Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the α2δ subunit of voltage-gated calcium channels
Hu, Tao,Stearns, Brian A.,Campbell, Brian T.,Arruda, Jeannie M.,Chen, Chixu,Aiyar, Jayashree,Bezverkov, Robert E.,Santini, Angelina,Schaffhauser, Herve,Liu, Wensheng,Venkatraman, Shankar,Munoz, Benito
, p. 2031 - 2034 (2004)
A novel class of 2H-pyrrolo[3,4-c]pyridazine ligands of the α2δ subunit of voltage-gated calcium channels is described. Compound 4a with high affinity toward α2δ was identified through structure-activity relationship studies of the l