608-94-6

Basic information

• Product Name: 2,3,6-Trichlorohydroquinone
• Synonyms: 2,3,5-Trichlorohydroquinone;2,3,6-Trichlorohydroquinone
• CAS NO: 608-94-6
• Molecular Formula: C₆H₃Cl₃O₂
• Molecular Weight: 213.45
• Mol File: 608-94-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 306.43°C (rough estimate)
• Flash Point: 123.9°C
• Appearance: /
• Density: 1.6568 (rough estimate)
• Vapor Pressure: 0.00213mmHg at 25°C
• Refractive Index: 1.4501 (estimate)
• CAS DataBase Reference: 2,3,6-Trichlorohydroquinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,6-Trichlorohydroquinone(608-94-6)
• EPA Substance Registry System: 2,3,6-Trichlorohydroquinone(608-94-6)

Safety Data

• Hazardous Substances Data: 608-94-6(Hazardous Substances Data)

Usage

General Description

2,3,6-Trichlorohydroquinone is a chemical compound that is a derivative of hydroquinone which is widely used in the manufacturing of photographic and medical chemicals. It is a white crystalline powder that is insoluble in water but soluble in organic solvents. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals and also as a stabilizer in the production of certain polymers. However, 2,3,6-Trichlorohydroquinone is considered to be a hazardous chemical and has been linked to skin and eye irritation, and may also be harmful if swallowed or inhaled. Therefore, proper safety measures and handling precautions should be followed when dealing with this chemical.

InChI:InChI=1/C6H3Cl3O2/c7-2-1-3(10)4(8)5(9)6(2)11/h1,10-11H

Upstream product

• 615-93-0 2,5-Dichloro-1,4-benzoquinone 
• 634-85-5 2,3,6-trichloro-1,4-benzoquinone 
• 71-43-2 benzene 
• 563-43-9 ethylaluminum dichloride 
• 5145-42-6 2,3-dichloro-1,4-benzoquinone 
• 89487-79-6 2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione 
• 7664-93-9 sulfuric acid 
• 7647-01-0 hydrogenchloride 
• 87-87-6 2,3,5,6-tetrachlorobenzene-1,4-diol 
• 7732-18-5 water 
• 5273-62-1 5,6-dichlorocyclohex-2-ene-1,4-dione 
• 1122-17-4 dichloromaleic acid anhydride 
• 39542-66-0 2,3-dichlorohydroquinone dimethyl ether 
• 933-75-5 2,3,6-trichlorophenol 

Downstream Products

• 125635-87-2 2,3,5-trichlorohydroquinone diacetate 
• 69653-71-0 2,3,5-trichloro-1,4-dimethoxybenzene 
• 608-93-5 pentachlorobenzene 
• 118-74-1 hexachlorobenzene 
• 118-75-2 chloranil 
• 46008-95-1 bromo-trichloro-[1,4]benzoquinone 
• 634-85-5 2,3,6-trichloro-1,4-benzoquinone 
• 3225-29-4 p-benzosemiquinone radical anion 
• 740782-07-4 2,4,5-trichloro-3,6-dihydroxy-benzenesulfonic acid 

Relevant articles and documents

Cycloacylation of chloro-substituted hydroquinone dimethyl ethers with dichloromaleic anhydride

Under the drastic conditions of Zahn—Ochwat cycloacylation of 2-chloroand 2,3-dichlorohydroquinones with dichloromaleic anhydride (a melt of anhydrous AlCl3 and NaCl, 185—195 °C), the substrates undergo various degrees of disproportionation, which reduces the yields of the target triand tetrachloronaphthazarins. Quantum chemical calculations showed that the cycloacylation in question proceeds as a double aromatic electrophilic substitution of the vicinal protons with the corresponding oxocarbenium ions (acylium cations).

S-Glutathionyl-(chloro)hydroquinone reductases: A novel class of glutathione transferases

Sphingobium chlorophenolicum completely mineralizes PCP (pentachlorophenol). Two GSTs (glutathione transferases), PcpC and PcpF, are involved in the degradation. PcpC uses GSH to reduce TeCH (tetrachloro-p- hydroquinone) to TriCH (trichlorop-hydroquinone)

Properties of chlorinated dihydroxybenzenes - components of pulp bleaching effluents

Gas chromatography and mass spectrometry data are given for the chlorodihydroxybenzenes which are components of wood pulp bleaching effluents and biologically-treated effluents, and are proposed intermediates in the chlorination of humic acids. The chlorohydroxybenzenes include the nine chlorocatechols, the six chlorohydroquinones and the seven known chlororesorcinols. The 22 chlorinated compounds were generally well separated on a phenyl methyl silicone column with the exception of three dichloro compounds. The chloro compounds with the same level of chlorine substitution were not able to be distinguished on the basis of their electron impact mass spectra.