61-28-9

Basic information

• Product Name: 1-ethyl-1,3-dihydro-2H-indol-2-one
• Synonyms: 2H-Indol-2-one, 1-ethyl-1,3-dihydro-; 1-Ethyl-2-indolinone; 1-Ethyloxindole; 2-Indolinone, 1-ethyl-; Ba 2778; N-Ethyloxindole; NSC 8893; 1-Ethyl-1,3-dihydro-2H-indol-2-one
• CAS NO: 61-28-9
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161.2004
• EINECS: 200-503-7
• Mol File: 61-28-9.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 352.6°C at 760 mmHg
• Flash Point: 172.9°C
• Density: 1.122g/cm³
• Vapor Pressure: 3.8E-05mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: 1-ethyl-1,3-dihydro-2H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ethyl-1,3-dihydro-2H-indol-2-one(61-28-9)
• EPA Substance Registry System: 1-ethyl-1,3-dihydro-2H-indol-2-one(61-28-9)

Safety Data

• Hazardous Substances Data: 61-28-9(Hazardous Substances Data)

Usage

General Description

1-Ethyl-1,3-dihydro-2H-indol-2-one, also known as 1-Ethyl-1,3-dihydroindol-2-one, is a chemical compound with the molecular formula C10H11NO. It is a colorless to pale yellow liquid that is commonly used as a fragrance and flavoring agent in the cosmetics and food industries. 1-ethyl-1,3-dihydro-2H-indol-2-one has a floral, sweet, and slightly fruity odor, making it a popular ingredient in perfumes, soaps, and lotions. It is also used in the production of various food products, including beverages, confections, and baked goods, to impart a pleasant aroma and taste. Additionally, 1-Ethyl-1,3-dihydro-2H-indol-2-one has been studied for its potential therapeutic applications, including its anti-inflammatory and analgesic properties. However, further research is needed to fully understand its pharmacological effects and safety profile.

Upstream product

• 59-48-3 2-oxoindole 
• 75-03-6 ethyl iodide 
• 76269-81-3 2-diazo-N-ethyl-N-phenylacetamide 
• 142612-52-0 N-ethyl-N-phenyl-α-(methoxycarbonyl)-α-diazoacetamide 
• 109686-91-1 1,3-Dihydro-3,3-bis(methylthio)-1-<1-(methylthio)ethyl>-2H-indol-2-on 
• 2444-36-2 2'-chloro-benzeneacetic acid 
• 75-04-7 ethylamine 
• 18698-97-0 ortho-bromophenylacetic acid 
• 103-69-5 N-ethyl-N-phenylamine 
• 91-56-5 indole-2,3-dione 
• 10604-59-8 N-Ethylindole 
• 157837-30-4 bromo-acetic acid-(N-ethyl-anilide) 
• 1399215-04-3 diethyl 1-ethyl-2-oxoindolin-3-yl phosphate 
• 5059-30-3 2-chloroindole-3-carboxaldehyde 

Downstream Products

• 141210-65-3 1-ethyl-(N,N-dimethyl)aminomethylene-2,3-dihydro-2-indolinoone 
• 141210-66-4 trans-1-ethyl-3-(dimethylaminomethylene)oxindole 
• 142272-22-8 1-ethyl-2,3-dihydro-5-nitro-2-oxo-N-phenyl-1H-indole-3-carboxamide 
• 142272-16-0 6-amino-9-ethyl-3-phenyl-1,3-oxazino<6,5-b>indole-2,4-(3H,9H)-dione 
• 142272-26-2 9-ethyl-6-nitro-3-phenyl-1,3-oxazino<6,5-b>indole-2,4-(3H,9H)-dione 
• 142272-24-0 1-Ethyl-5-nitro-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid (4-fluoro-phenyl)-amide 
• 142272-25-1 1-Ethyl-5-nitro-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid (4-methoxy-phenyl)-amide 
• 142272-23-9 1-Ethyl-5-nitro-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid (4-cyano-phenyl)-amide 
• 142272-28-4 9-Ethyl-3-(4-fluoro-phenyl)-6-nitro-9H-[1,3]oxazino[6,5-b]indole-2,4-dione 
• 142272-29-5 9-Ethyl-3-(4-methoxy-phenyl)-6-nitro-9H-[1,3]oxazino[6,5-b]indole-2,4-dione 
• 142272-27-3 4-(9-Ethyl-6-nitro-2,4-dioxo-4,9-dihydro-[1,3]oxazino[6,5-b]indol-3-yl)-benzonitrile 
• 124137-08-2 3-acetyl-1-ethyl-3-(2,5-bis-benzenesulfonylamino-phenyl)-indolin-2-one 
• 104019-07-0 1-ethyl-5-benzoyloxindole 

Relevant articles and documents

Photochemical 1,3-migration of the hydroxyl group in 1-alkyl-3-hydroxyoxindoles

Irradiation of 1-alkyl-3-hydroxyoxindoles in degassed solutions afforded 1-alkyl-4-hydroxyoxindoles via 1,3-migration of the hydroxyl group together with 1-alkyloxindoles.

New donor-π-acceptor type triazatruxene derivatives for highly efficient dye-sensitized solar cells

A new class of organic dyes based on triazatruxene have been designed and synthesized for dye-sensitized solar cells. The photoelectronic properties of these donor-π-acceptor dyes can be tuned by changing π-conjugated linkers. The best performance was found for triazatruxene dye TD1, wherein, with thiophene as the conjugated linker and cyanoacrylic acid as the acceptor, a power conversion efficiency up to 6.10% was achieved.

A novel methodology for the efficient synthesis of 3-monohalooxindoles by acidolysis of 3-phosphate-substituted oxindoles with haloid acids

A novel method for the synthesis of 3-monohalooxindoles by acidolysis of isatin-derived 3-phosphate-substituted oxindoles with haloid acids was developed. This synthetic strategy involved the preparation of 3-phosphate-substituted oxindole intermediates and SN1 reactions with haloid acids. This new procedure features mild reaction conditions, simple operation, good yield, readily available and inexpensive starting materials, and gram-scalability.

Synthesis of Oxindole Derivatives via Intramolecular C–H Insertion of Diazoamides Using Ru(II)-Pheox Catalyst

This work presented the efficient intramolecular aromatic C–H insertion of diazoacetamide. The 1a–1o diazo compounds (except for 1k) were converted into their corresponding oxindoles via an intramolecular C–H insertion reaction in the presence of a Ru catalyst. The Ru-Pheox catalyst was shown to be highly efficient in this transformation in terms of the regioselectivity, producing the desired products in excellent yield (99%). The efficiency of the Ru catalyst reached 580 (TON) and 156 min?1 (TOF).