614717-91-8

Basic information

• Product Name: 2-(3-broMophenyl)iMidazole[4,5f][1,10]phenanthroline
• Synonyms: 2-(3-broMophenyl)iMidazole[4,5f][1,10]phenanthroline
• CAS NO: 614717-91-8
• Molecular Formula: C₁₉H₁₁BrN₄
• Molecular Weight: 375.22
• Mol File: 614717-91-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3-broMophenyl)iMidazole[4,5f][1,10]phenanthroline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-broMophenyl)iMidazole[4,5f][1,10]phenanthroline(614717-91-8)
• EPA Substance Registry System: 2-(3-broMophenyl)iMidazole[4,5f][1,10]phenanthroline(614717-91-8)

Safety Data

• Hazardous Substances Data: 614717-91-8(Hazardous Substances Data)

Upstream product

• 27318-90-7 1,10-phenanthroline-5,6-dione 
• 3132-99-8 m-bromobenzoic aldehyde 

Relevant articles and documents

Synthesis, characterization and biological activities of ciprofloxacin drug based metal complexes

The interaction of small molecules with DNA has attracted a great deal of attention. Mixed ligand copper(II) complexes of type [Cu(cpf)(Ln)Cl] [cpf = ciprofloxacin, Ln = phenanthroline derivatives] were synthesized and characterized by elemental analysis, reflectance, IR and mass spectra. Viscosity measurements, absorption titration and DNA melting temperature studies were employed to determine the mode of binding of complexes with DNA. DNA cleavage study showed better cleaving ability of the complexes compare to metal salts and standard drug. The SOD mimic study showed IC 50 value of complexes in the range of 0.95 to 1.75 μM. Antibacterial activity was assayed against selective Gram(-ve) and Gram(+ve) microorganisms.