615-56-5Relevant articles and documents
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Schiff,F.
, p. 347 (1890)
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Regioselectivity in the aryne cross-coupling of aryllithiums with functionalized 1,2-dibromobenzenes
Diemer, Vincent,Begaud, Manon,Leroux, Frederic R.,Colobert, Fracoise
experimental part, p. 341 - 354 (2011/02/28)
Tri- and tetrasubstituted ortho-bromobiaryls have been synthesized in good-to-excellent yields by aryne cross-coupling reactions starting from 1,3-dimethoxybenzene and functionalized 1,2-dibromobenzenes. This study outlines the influence of the 1,2-dibromobenzene precursor as well as the reaction temperature on the outcome of the aryl-aryl bond formation and indicates, in the case of dissymmetrical benzyne precursors, how structural parameters (electronic effects, steric hindrance, temperature, etc.) control the regioselectivity of the aryne cross-coupling reactions. A wide range of o,o′-tri- and-tetrasubstituted biphenyls have been prepared by a transition-metal-free "aryne" cross-coupling starting from 2,6-dimethoxyphenyllithium and various functionalized 1,2-dibromobenzenes. Mechanistic investigations outline the key parameters that govern both the aryl-aryl bond formation and the regioselectivity of the reaction with dissymmetrical aryne precursors. Copyright
Polybrominated diphenyl ethers (BDEs); preparation of reference standards and fluorinated internal analytical standards
Liu, Huiling,Bernhardsen, Monica,Fiksdahl, Anne
, p. 3564 - 3572 (2007/10/03)
Four new difluorinated tetra- and pentabromo BDE internal standards for GC-MS/GC-ECD analysis, 2F-BDE 47, 2F-BDE 85, 2F-BDE 99 and 2F-BDE 119, have been prepared in 98-99.0% purity, mainly by coupling of the new tribromodifluorophenols (19-21) and symmetr
