61696-79-5

Basic information

• Product Name: 1(2H)-Naphthalenone, 3,4-dihydro-3-(4-methoxyphenyl)-
• CAS NO: 61696-79-5
• Molecular Formula: C17H16O2
• Molecular Weight: 252.313
• Mol File: 61696-79-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1(2H)-Naphthalenone, 3,4-dihydro-3-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Naphthalenone, 3,4-dihydro-3-(4-methoxyphenyl)-(61696-79-5)
• EPA Substance Registry System: 1(2H)-Naphthalenone, 3,4-dihydro-3-(4-methoxyphenyl)-(61696-79-5)

Safety Data

• Hazardous Substances Data: 61696-79-5(Hazardous Substances Data)

Usage

General Description

1(2H)-Naphthalenone, 3,4-dihydro-3-(4-methoxyphenyl)- is a chemical compound that belongs to the class of naphthalenones, which are organic compounds with a naphthalene backbone. It is also known by the name "diosmetin ketone" and is used in the synthesis of various pharmaceuticals and natural products. 1(2H)-Naphthalenone, 3,4-dihydro-3-(4-methoxyphenyl)- is a derivative of naphthalenone, with a hydroxyl group and a methoxyphenyl substituent at the 3 and 4 positions, respectively. It has been studied for its potential medicinal properties, particularly as an antioxidant and anti-inflammatory agent. Additionally, it has shown to have potential as a nutraceutical and functional food ingredient due to its beneficial biological activities.

Upstream product

• 118806-78-3 3-(4-methoxyphenyl)-4-phenylbutanoic acid 
• 1023-17-2 4-methoxyphenyl benzyl ketone 
• 100-66-3 methoxybenzene 
• 103-82-2 phenylacetic acid 
• 716-43-8 dimethyl homophthalate 
• 24393-56-4 ethyl p-methoxycinnamate 
• 123-11-5 4-methoxy-benzaldehyde 
• 7443-25-6 dimethyl 2-(4-methoxybenzylidene)malonate 
• 1333110-92-1 C₂₀H₂₂O₅ 
• 118806-75-0 3-p-methoxyphenyl-2-carboxy-4-phenylbutyric acid 
• 6768-23-6 diethyl-2-(4-methoxybenzylidene)malonate 
• 171818-87-4 3-hydroxy-3-(4-methoxy-phenyl)-4-phenyl-butyric acid ethyl ester 
• 171818-88-5 ethyl 3-(4-methoxyphenyl)-4-phenylbutanoate 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 90035-32-8 3-(4-hydroxyphenyl)-3,4-dihydronaphthalen-1(2H)-one 
• 104563-61-3 cis-4-hydroxy-3-[1,2,3,4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyl]-1-naphthyl]coumarin 
• 104563-61-3 trans-4-hydroxy-3-[1,2,3,4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyl]-1-naphthyl]coumarin 
• 121511-08-8 3-(4-Methoxy-phenyl)-3,4-dihydro-2H-naphthalen-1-one oxime 
• 121511-12-4 3-(4-methoxyphenyl)naphthalen-1-amine 
• 807609-63-8 1-bromo-3-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-1,2,3,4-tetrahydro-naphthalene 
• 287974-84-9 3-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-3,4-dihydro-2H-naphthalen-1-one 
• 103772-30-1 1,2,3,4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyl]naphthalen-1-ol 
• 807609-62-7 3-(p-bromobiphenyl-4-yl)-1,2,3,4-tetrahydronaphthalen-1-ol 

Relevant articles and documents

Origin of stereocontrol in guanidine-bisurea bifunctional organocatalyst that promotes α-hydroxylation of tetralone-derived β-ketoesters: Asymmetric synthesis of β- And γ-substituted tetralone derivatives via organocatalytic oxidative kinetic resolution

The mechanism of asymmetric α-hydroxylation of tetralone-derived β-ketoesters with guanidine-bisurea bifunctional organocatalyst in the presence of cumene hydroperoxide (CHP) was examined by means of DFT calculations to understand the origin of the stereo

Simple synthesis and biological evaluation of flocoumafen and its structural isomers

Simple synthesis and biological properties of flocoumafen 1 and its structural isomers are described. The key synthetic strategies involve Knoevenagel condensation, Grignard reaction, intramolecular ring cyclization and coupling reaction. Flocoumafen 1 was easily separated into cis and trans forms using flash column chromatography. They were then evaluated for suppression of LPS-induced NO generation and anti-excitotoxicity in vitro. It was found that the trans-flocoumafen was potent suppressor of NO generation with the concentration of 10 μM in vitro, while no significant effect for neurotoxicity in cultured cortical neurons. Indian Academy of Sciences.

Synthesis of 3-Aryl-1-tetralones

A new method for the synthesis of 3-aryl-1-tetralones is presented.The tetralones synthesised have been characterised by elemental analysis and soectral data.