6200-60-8 Usage
General Description
IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID, also known as IPA-3, is a chemical compound with potential anti-cancer and anti-inflammatory properties. It is a specific inhibitor of the enzyme PAK1, which is involved in various cellular processes including cell motility, proliferation, and survival. By inhibiting PAK1, IPA-3 has the potential to disrupt cancer cell growth and metastasis. Additionally, IPA-3 has been shown to reduce the production of inflammatory cytokines, suggesting its potential in treating inflammatory diseases. Research on the potential therapeutic applications of IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID is ongoing, and it may hold promise as a drug candidate for the treatment of cancer and inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 6200-60-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,0 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6200-60:
(6*6)+(5*2)+(4*0)+(3*0)+(2*6)+(1*0)=58
58 % 10 = 8
So 6200-60-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H21F3N2O3S/c1-13(2)14-7-9-16(10-8-14)23-18(25)12-24(28(3,26)27)17-6-4-5-15(11-17)19(20,21)22/h4-11,13H,12H2,1-3H3,(H,23,25)
6200-60-8Relevant articles and documents
Discovery of potent colony-stimulating factor 1 receptor inhibitors by replacement of hinge-binder moieties
Lee, Jung Wuk,Park, Jiwon,Kim, Jina,Kim, Jihyung,Choi, Changyu,Min, Kyung Hoon
, (2021/03/14)
Tumor-associated macrophages (TAMs) are predominantly associated with tumor growth. Colony-stimulating factor 1 receptor (CSF1R) acts as a key regulator of TAM survival and differentiation and is a molecular target for cancer therapies. Herein, novel CSF1
