62234-37-1Relevant articles and documents
Synthesis of (R)- and (S)-2,3-diaminopropyl sulfate: Mechanism based inhibition of glutamate 1-semialdehyde aminomutase
Khayer, Khurshida,Jenn, Thierry,Akhtar, Mahmoud,John, Robert,Gani, David
, p. 1637 - 1641 (2007/10/03)
A short synthesis of each enantiomer of 2,3-diaminopropyl hydrogensulfate is described starting from (2R)- and (2S)-asparagine. The compounds serve as inhibitors for pyridoxal 5'-phosphate-dependent (2S)- glutamate 1-semialdehyde aminotransferase, a target for selective herbicides and antibacterial agents on the tetrapyrrole biosynthetic pathway. The (2R)- enantiomer, as predicted, serves as a potent irreversible inactivator. (C) 2000 Elsevier Science Ltd.
Substituted urido amino and imino acids and esters
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, (2008/06/13)
Compounds of the formula STR1 wherein X is various imino or amino acids or esters are disclosed. These compounds possess angiotensin converting enzyme inhibition activity and depending upon the definition of X also possess enkephalinase inhibition activit
Conversion of serine to stereochemically pure β-substituted α-amino acids via β-lactones
Arnold,Kalantar,Vederas
, p. 7105 - 7109 (2007/10/02)
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