625-61-6

Basic information

• Product Name: ethylsulfanylmethanethioamide
• Synonyms: ethylsulfanylmethanethioamide;Dithiocarbamic acid ethyl ester;Carbamodithioic acid,ethyl ester
• CAS NO: 625-61-6
• Molecular Formula: C₃H₇NS₂
• Molecular Weight: 121.22
• Mol File: 625-61-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 199.2 °C at 760 mmHg
• Flash Point: 74.3 °C
• Appearance: /
• Density: 1.203 g/cm³
• Vapor Pressure: 0.346mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: ethylsulfanylmethanethioamide(CAS DataBase Reference)
• NIST Chemistry Reference: ethylsulfanylmethanethioamide(625-61-6)
• EPA Substance Registry System: ethylsulfanylmethanethioamide(625-61-6)

Safety Data

• Hazardous Substances Data: 625-61-6(Hazardous Substances Data)

Usage

General Description

Ethylsulfanylmethanethioamide is a chemical compound with the molecular formula C4H10N2S3. It is an organosulfur compound that contains both ethyl and thioamide functional groups. It is commonly used as a building block in organic synthesis and chemical research. Ethylsulfanylmethanethioamide is also known for its potential biological activities, including antibacterial and antifungal properties. Additionally, it has been studied for its potential applications in the pharmaceutical industry, specifically for the development of new medicines and drugs. Overall, ethylsulfanylmethanethioamide is a versatile and important chemical compound with various potential uses in both research and industry.

InChI:InChI=1/C3H7NS2/c1-2-6-3(4)5/h2H2,1H3,(H2,4,5)

Upstream product

• 513-74-6 ammonium dithiocarbamate 
• 75-03-6 ethyl iodide 
• 542-90-5 ethyl isothiocyanate 
• 7783-06-4 hydrogen sulfide 
• 7647-01-0 hydrogenchloride 
• 6322-61-8 N-acetyldithiocarbamic acid ethyl ester 

Downstream Products

• 857419-85-3 1,5-di-pyrrol-2-yl-3-thia-pentane-1,5-dione 
• 6322-61-8 N-acetyldithiocarbamic acid ethyl ester 
• 5316-74-5 2-ethylsulfanyl-4-phenyl-thiazole 
• 21076-08-4 2-methyl-1-phenyl thiosemicarbazide 
• 75-08-1 ethanethiol 
• 1455272-68-0 4-(4-methoxyphenyl)-5-(4-chlorophenyl)-2-(ethylthio)-thiazole 
• 28126-47-8 ethyl phenyl(p-toluenesulfonyl)methylcarbamodithioate 
• 953822-10-1 ethyl 3-phenyl-1-(p-toluenesulfonyl)propylcarbamodithioate 
• 1147550-11-5 ammonium thiocyanate 
• 75-15-0 carbon disulfide 
• 542-90-5 ethyl isothiocyanate 
• 7783-06-4 hydrogen sulfide 
• 21076-24-4 2-Ethyl-1-phenyl-thiosemicarbazid 

Relevant articles and documents

Synthesis, cytotoxic evaluation, and molecular docking study of 4,5-diaryl-thiazole-2-thione analogs of combretastatin A-4 as microtubule-binding agents

A series of combretastatin A-4 analogs in which cis-olefinic bond replaced by thiazole ring were prepared by reaction of α-bromo-1,2-(p-substituted) diaryl-1-ethanones and dithiocarbamate derivatives. The cytotoxicity of these compounds was determined against three cancer cell lines (HT-29), (MCF-7), (AGS) as well as fibroblastic cell line (NIH-3T3) using MTT assay. Inhibition of tubulin polymerization for some potent compounds was evaluated. These biological studies proved that 6j and 6o were the most potent compounds in this series. Furthermore 2-(methylthio)-substituted compounds show moderate or no activity. Docking studies involving 6j and 6o demonstrated that this analogs could be successfully docked in the colchicine binding site of α,β-tubulin.