625111-39-9

Basic information

• Product Name: (1S,3R,4S,7R)-7-benzyloxy-3-(6-N-benzoyladenin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane
• Synonyms: (1S,3R,4S,7R)-7-benzyloxy-3-(6-N-benzoyladenin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane
• CAS NO: 625111-39-9
• Molecular Weight: 551.58
• Mol File: 625111-39-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1S,3R,4S,7R)-7-benzyloxy-3-(6-N-benzoyladenin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,3R,4S,7R)-7-benzyloxy-3-(6-N-benzoyladenin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane(625111-39-9)
• EPA Substance Registry System: (1S,3R,4S,7R)-7-benzyloxy-3-(6-N-benzoyladenin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane(625111-39-9)

Safety Data

• Hazardous Substances Data: 625111-39-9(Hazardous Substances Data)

Upstream product

• 341536-45-6 9-[2-O-acetyl-5-O-benzoyl-4-C-[(benzoyloxy)methyl]-3-O-benzyl-α-L-threo-pentofuranosyl]-6-N-benzoyladenine 
• 341536-46-7 9-[2-O-acetyl-5-O-benzoyl-4-C-[(benzoyloxy)methyl]-3-O-benzyl-α-L-erythro-pentofuranosyl]-6-N-benzoyladenine 
• 673456-34-3 C₃₉H₃₃N₅O₈ 
• 341536-47-8 9-[3-O-benzyl-4-C-(hydroxymethyl)-α-L-erythro-pentofuranosyl]-6-N-benzoyladenine 
• 230631-16-0 1,2-Di-O-acetyl-5-O-benzoyl-4-C-benzoyloxymethyl-3-O-benzyl-L-threo-pentofuranose 
• 4005-49-6 N-benzoyladenine 
• 72261-44-0 1,2-O-isopropylidene-3-O-benzyl-4-C-(hydroxymethyl)-β-L-threo-pento-1,4-furanose 
• 341536-48-9 9-[3-O-benzyl-5-O-(methanesulfonyl)-4-C-[[(methanesulfonyl)oxy]methyl]-α-L-erythro-pentofuranosyl]-6-N-benzoyladenine 
• 410076-94-7 9-[2-O-acetyl-3-O-benzyl-5-O-(methanesulfonyl)-4-C-[[(methanesulfonyl)oxy]methyl]-α-L-threo-pentofuranosyl]-6-N-benzoyladenine 
• 410076-96-9 9-(2-O-acetyl-3-O-benzyl-5-O-(methanesulfonyl)-4-C-[[(methanesulfonyl)oxy]methyl]-α-L-erythro-pentofuranosyl)-6-N-benzoyladenine 
• 410076-95-8 9-(3-O-benzyl-5-O-(methanesulfonyl)-4-C-[[(methanesulfonyl)oxy]methyl]-α-L-threo-pentofuranosyl)-6-N-benzoyladenine 
• 410076-93-6 3-O-benzyl-1,2-di-O-acetyl-5-O-(methylsulfonyl)-4-C-(methylsulfonyloxymethyl)-α,β-L-threo-pentofuranose 
• 410076-92-5 3-O-benzyl-5-O-(methanesulfonyl)-4-C-[[(methanesulfonyl)oxy]methyl]-1,2-O-isopropylidene-β-L-threo-pentofuranose 

Downstream Products

• 341536-49-0 (1R,3R,4S,7R)-3-(6-N-benzoyladenin-9-yl)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptane 
• 303183-65-5 (1R,3R,4S,7R)-3-(6-N-benzoyladenin-9-yl)-7-benzyloxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptane 
• 341536-51-4 (1S,3R,4S,7R)-1-[[(4,4'-dimethoxytrityl)oxy]methyl]-7-hydroxy-3-(6-N-benzoyladenin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane 
• 206055-79-0 (1S,3R,4S,7R)-7-[2-cyanoethoxy(diisopropylamino)phosphinoxy]-1-[[(4,4'-dimethoxytrityl)oxy]methyl]-3-(6-N-benzoyladenin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane 
• 410076-88-9 (1S,3R,4S,7R)-1-(acetoxymethyl)-3-(6-N-benzoyladenin-9-yl)-7-benzyloxy-2,5-dioxabicyclo[2.2.1]heptane 

Relevant articles and documents

SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES

The invention relates to a novel strategy for the synthesis of Locked Nucleic Acid derivatives, such as α-L-oxy-LNA, amino-LNA, α-L-amino-LNA, thio-LNA, α-L-thio-LNA, seleno-LNA and methylene LNA, which provides scalable high yielding reactions utilising

The adenine derivative of α-L-LNA (α-L-ribo configured locked nucleic acid): Synthesis and high-affinity hybridization towards DNA, RNA, LNA and α-L-LNA complementary sequences

Synthesis of a 9-mer α-L-LNA (α-L-ribo configured locked nucleic acid) containing three 9-(2-O,4-C-methylene-α-L-ribofuranosyl)adenine nucleotide monomer(s) has been accomplished. The work involved synthesis of the bicyclic adenine nucleoside via a conden