673456-34-3Relevant articles and documents
&α-L-ribo-Configured Locked Nucleic Acid (&α-L-LNA): Synthesis and Properties
Soerensen, Mads D.,Kvaernoe, Lisbet,Bryld, Torsten,Hakansson, Anders E.,Verbeure, Birgit,Gaubert, Gilles,Herdewijn, Piet,Wengel, Jesper
, p. 2164 - 2176 (2002)
The syntheses of monomeric nucleosides and 3'-O-phosphoramidite building blocks en route to α-L-ribo-configured locked nucleic acids (α-L-LNA), composed entirely of α-L-LNA monomers (α-L-ribo configuration) or of a mixture of α-L-LNA and DNA monomers (β-D
The adenine derivative of α-L-LNA (α-L-ribo configured locked nucleic acid): Synthesis and high-affinity hybridization towards DNA, RNA, LNA and α-L-LNA complementary sequences
Hakansson, Anders E.,Wengel, Jesper
, p. 935 - 938 (2007/10/03)
Synthesis of a 9-mer α-L-LNA (α-L-ribo configured locked nucleic acid) containing three 9-(2-O,4-C-methylene-α-L-ribofuranosyl)adenine nucleotide monomer(s) has been accomplished. The work involved synthesis of the bicyclic adenine nucleoside via a conden