62708-56-9 Usage
Description
(-)-Dibenzoyl-L-tartaric acid monohydrate is a white to light yellow crystalline powder that serves as a crucial intermediate in the pharmaceutical and agrochemical industries. It is also utilized as a chiral auxiliary in organic synthesis and as a resolution agent in the synthesis of rameleton. Its chemical properties and applications make it a valuable compound in the development of various products.
Uses
Used in Pharmaceutical Industry:
(-)-Dibenzoyl-L-tartaric acid monohydrate is used as an intermediate for the development and production of pharmaceutical products. It plays a vital role in the synthesis of various drugs, contributing to the overall effectiveness and quality of the final product.
Used in Agrochemical Industry:
In the agrochemical industry, (-)-Dibenzoyl-L-tartaric acid monohydrate is employed as an intermediate in the synthesis of agrochemicals, such as pesticides and fertilizers. Its use in this industry helps improve the efficiency and effectiveness of these products, ultimately benefiting agricultural practices.
Used as a Chiral Auxiliary in Organic Synthesis:
(-)-Dibenzoyl-L-tartaric acid monohydrate is used as a chiral auxiliary in organic synthesis, which is essential for the production of enantiomerically pure compounds. This application is crucial in the development of pharmaceuticals, as many drugs exhibit different effects depending on their enantiomeric form.
Used as a Resolution Agent in the Synthesis of Rameleton:
(-)-Dibenzoyl-L-tartaric acid monohydrate serves as a resolution agent in the synthesis of rameleton, a compound with potential applications in various fields. Its use in this process helps ensure the production of high-quality rameleton.
Used as a Chiral Resolving Agent:
(-)-Dibenzoyl-L-tartaric acid monohydrate may be used as a chiral resolving agent for the resolution of racemic bioactive compounds, such as (±)-3-(3-hydroxyphenyl)-N-(1-propyl)-piperidine and (±)-2-(5,6-dimethoxy-1,2,3,4-tetrahydro-1-naphthyl)-imidazoline. This application allows for the isolation of the corresponding (-)-enantiomeric forms, which can be crucial in the development of enantiomerically pure drugs with specific therapeutic effects.
Purification Methods
Crystallise the acid from water (18g from 400 mL boiling H2O) and stir vigorously while cooling in order to obtain crystals; otherwise an oil will separate which solidifies on cooling. Dry it in a vacuum desiccator over KOH/H2SO4 (yield 16.4g) as monohydrate, m 88-89o. It crystallises from xylene as the anhydrous acid, m 173o (150-153o). It does not crystallise from *C6H6, toluene, *C6H6/pet ether (oil), or CHCl3/pet ether. [Butler & Cretcher J Am Chem Soc 55 2605 1933, Acs et al. Tetrahedron 41 2465 1985, R(+) Beilstein 9 IV 557, S(-) Beilstein 9 III 870.]
Check Digit Verification of cas no
The CAS Registry Mumber 62708-56-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,7,0 and 8 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 62708-56:
(7*6)+(6*2)+(5*7)+(4*0)+(3*8)+(2*5)+(1*6)=129
129 % 10 = 9
So 62708-56-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H14O8.H2O/c19-15(20)13(25-17(23)11-7-3-1-4-8-11)14(16(21)22)26-18(24)12-9-5-2-6-10-12;/h1-10,13-14H,(H,19,20)(H,21,22);1H2