62731-45-7

Basic information

• Product Name: 3-Pentanone, 1-hydroxy-1,5-diphenyl-
• CAS NO: 62731-45-7
• Molecular Formula: C17H18O2
• Molecular Weight: 254.329
• Mol File: 62731-45-7.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 3-Pentanone, 1-hydroxy-1,5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pentanone, 1-hydroxy-1,5-diphenyl-(62731-45-7)
• EPA Substance Registry System: 3-Pentanone, 1-hydroxy-1,5-diphenyl-(62731-45-7)

Safety Data

• Hazardous Substances Data: 62731-45-7(Hazardous Substances Data)

Upstream product

• 2550-26-7 4-Phenyl-2-butanone 
• 100-52-7 benzaldehyde 
• 66581-82-6 4-phenyl-3-(trimethylsilyl)-2-butanone 
• 352276-27-8 1-iodo-4-phenylbutan-2-one 
• 97394-41-7 S-(4-nitrophenyl) 3-phenylpropanethioate 
• 31729-70-1 bis(iodozinc)methane 
• 59417-89-9 4-phenyl-2-(trimethylsiloxy)-1-butene 
• 100-42-5 styrene 
• 121407-63-4 5-Phenyl-3-phenylsulfanylmethyl-4,5-dihydro-isoxazole 
• 263888-15-9 3-phenethyl-5-phenyl-4,5-dihydroisoxazole 

Downstream Products

• 1036384-65-2 2-(dimethyl-λ4-sulfanylidene)-1,5-diphenyl-pentane-1,3-dione 
• 1036385-20-2 (R)-1-hydroxy-1,5-diphenyl-pentan-3-one 
• 108887-64-5 (S)-1-hydroxy-1,5-diphenyl-pentan-3-one 
• 62510-08-1 1,5-diphenyl-1-penten-3-one 

Relevant articles and documents

Chemo- and regioselective preparation of zinc enolate from thiol esters by palladium catalyzed cross-coupling reaction

The palladium catalyzed cross-coupling reaction of thiol esters with bis(iodozincio)methane or 1,1-bis(iodozincio)ethane gave Reformatsky-type enolates. They can react with some electrophiles to give the corresponding adducts and were also trapped by silylation reagents to afford silyl enol ethers. As the method applicable to the thiol ester carrying ketone moiety, it afforded zinc enolates carrying ketone in the same molecule.

Synthesis and evaluation of estrogen agonism of diaryl 4,5- dihydroisoxazoles, 3-hydroxyketones, 3-methoxyketones, and 1,3-diketones: A compound set forming a 4D molecular library

In this paper, the preparation and systematic evaluation of estrogen receptor α (ERα) and estrogen receptor β (ERβ) activities of some diaryl-1,3-diones and their synthetic intermediates, diaryl-4,5-dihydroisoxazoles, diaryl-3-hydroxyketones, diaryl-3-met

Stereoselective crossed aldol reaction via boron enolates generated from α-iodo ketones and 9-borabicyclo[3.3.1]nonane

Boron enolates were in situ-generated reductively by treating various α-iodo ketones such as 2-iodo-1-phenylpropan-1-one, 2-iodo-1-(4-methoxyphenyl)propan-1-one, 2-iodopentan-3-one, 2-iodo-2-methyl-1-phenylpropan-1-one, 3,4-dihydro-2-iodo-1(2H)-naphthalenone, 2-iodo-1-phenylethan-1-one and 1-iodo-4-phenylbutan-2-one with 9-borabicyclo[3.3.1]nonane (9-BBN). Aldols were produced in good yields with good to high diastereoselectivities by subsequent reaction of boron enolates thus formed with various aldehydes. Several boron enolates derived from α-iodo ketones and pinacolatoborane were successfully isolated by distillation, though the yields were rather moderate.