6299-66-7Relevant articles and documents
CATALYTIC CARBOXYLATION OF ACTIVATED ALKANES AND/OR OLEFINS
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Page/Page column 65; 66; 67, (2018/02/28)
The present invention relates to a method of reacting starting materials with an activating group, namely alkanes carrying a leaving group and/or olefins, with carbon dioxide under transition metal catalysis to give carboxyl group-containing products. It is a special feature of the method of the present invention that the carboxylation predominantly takes place at a preferred position of the molecule irrespective of the position of the activating group. The carboxylation position is either an aliphatic terminus of the molecule or it is a carbon atom adjacent to a carbon carrying an electron withdrawing group. The course of the reaction can be controlled by appropriately choosing the reaction conditions to yield the desired regioisomer.
AMIDE COMPOUND AND MEDICINAL USE THEREOF
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Page/Page column 79, (2013/02/27)
A compound of formula [I-W]: wherein each symbol is as defined in the description, or a pharmaceutically acceptable salt thereof.
PYRIDAZINONE GLUCOKINASE ACTIVATORS
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Page/Page column 46-47, (2009/10/30)
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.