630121-86-7

Basic information

• Product Name: tert-Butyl 3-(((trifluoroMethyl)sulfonyl)oxy)-2,5-dihydro-1H-pyrrole-1-carboxylate
• Synonyms: tert-Butyl 3-(((trifluoroMethyl)sulfonyl)oxy)-2,5-dihydro-1H-pyrrole-1-carboxylate
• CAS NO: 630121-86-7
• Molecular Formula: C₁₀H₁₄F₃NO₅S
• Molecular Weight: 317.2820696
• Mol File: 630121-86-7.mol
• Article Data: 36

Chemical Properties

• Boiling Point: 344.6±42.0 °C(Predicted)
• Appearance: /
• Density: 1.43±0.1 g/cm3(Predicted)
• PKA: -4.36±0.40(Predicted)
• CAS DataBase Reference: tert-Butyl 3-(((trifluoroMethyl)sulfonyl)oxy)-2,5-dihydro-1H-pyrrole-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 3-(((trifluoroMethyl)sulfonyl)oxy)-2,5-dihydro-1H-pyrrole-1-carboxylate(630121-86-7)
• EPA Substance Registry System: tert-Butyl 3-(((trifluoroMethyl)sulfonyl)oxy)-2,5-dihydro-1H-pyrrole-1-carboxylate(630121-86-7)

Safety Data

• Hazardous Substances Data: 630121-86-7(Hazardous Substances Data)

Usage

General Description

Tert-Butyl 3-(((trifluoroMethyl)sulfonyl)oxy)-2,5-dihydro-1H-pyrrole-1-carboxylate is a complex organic compound with a molecular formula of C11H15F3NO5S. It is a pyrrole derivative containing a tert-butyl ester group and a trifluoromethylsulfonyl oxy functional group. This chemical is commonly used as a reagent in organic synthesis and pharmaceutical research. It has potential applications as a building block for the preparation of various compounds, including pharmaceuticals and agrochemicals. This chemical may also be used as an intermediate in the synthesis of other organic compounds.

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 101385-93-7 3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 103057-44-9 N-(tert-butoxycarbonyl)-3-hydroxypyrrolidine 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 145100-51-2 N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulphonyl]methanesulphonamide 

Downstream Products

• 912971-58-5 tert-butyl 3-(2-(2-methoxyphenyl)-1H-indol-5-yl)-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 212127-83-8 tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dihydropyrrole-1-carboxylate 
• 1393901-75-1 tert-butyl 3-(4-nitrophenyl)-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 1094217-59-0 1-tert-butoxycarbonyl-3-(3-hydroxyphenyl)pyrrolidine 
• 1204331-72-5 3-(4-carboxy-2-trifluoromethyl-phenyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1204331-71-4 3-(4-carboxy-2-trifluoromethyl-phenyl)-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester 
• 1204331-70-3 3-(4-cyano-2-trifluoromethyl-phenyl)-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

PURINES AND METHODS OF THEIR USE

Disclosed are compounds useful in the treatment of neurological disorders. The compounds described herein, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological diseases.

Substituted aza five-membered ring derivative and application thereof in medicine

The invention discloses a substituted aza-five-membered ring derivative and application thereof to medicines. , The invention provides a substituted aza five-membered ring compound or a stereoisomer, a tautomer, an oxynitride, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and a pharmaceutical composition containing the compound of the present invention. The invention also discloses application of the compound or the pharmaceutical composition of the compound in preparation of a medicament for treating PDE4 related diseases such as atopic dermatitis (AD) or chronic obstructive pulmonary disease (COPD).

INDOLO HEPTAMYL OXIME ANALOGUE AS PARP INHIBITOR

Disclosed is a type of indolo heptamyl oxime compounds as a PARP inhibitor. Specifically disclosed are a compound as represented by formula (II) and a pharmaceutically acceptable salt thereof.