63307-15-3

Basic information

• Product Name: 2-Butanone, 4-(2,3-dimethoxyphenyl)-1-(methylsulfinyl)-
• CAS NO: 63307-15-3
• Molecular Formula: C13H18O4S
• Molecular Weight: 270.35
• Mol File: 63307-15-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Butanone, 4-(2,3-dimethoxyphenyl)-1-(methylsulfinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 4-(2,3-dimethoxyphenyl)-1-(methylsulfinyl)-(63307-15-3)
• EPA Substance Registry System: 2-Butanone, 4-(2,3-dimethoxyphenyl)-1-(methylsulfinyl)-(63307-15-3)

Safety Data

• Hazardous Substances Data: 63307-15-3(Hazardous Substances Data)

Upstream product

• 15854-60-1 methyl 3-(2,3-dimethoxyphenyl)propenoate 
• 7345-82-6 trans-2,3-dimethoxycinnamic acid 
• 65953-99-3 methyl 3-(2,3-dimethoxyphenyl)propanoate 
• 67-68-5 dimethyl sulfoxide 
• 10538-48-4 2,3-dimethoxyhydrocinnamic acid 

Downstream Products

• 52644-01-6 5,6-dimethoxy-2-tetralone 

Relevant articles and documents

Synthesis and anticholinesterase activity of huperzine a analogues containing phenol and catechol replacements for the pyridone ring

Based upon modeling results obtained using the crystal structure of huperzine A in complex with acetylcholinesterase (AChE), two novel analogues of this potent AChE inhibitor were designed with phenol or catechol rings replacing the pyridone ring. From the modeling studies, the catechol analogue appeared capable of replacing one of the crystallographic waters bridging huperzine with Tyr 130 and Glu 199 of AChE. The synthesis of these materials by use of a palladium catalyzed bicycloannulation strategy is detailed together with the results of AChE inhibition assays.