63444-54-2Relevant articles and documents
Synthesis of 2-Arylpropionaldehydes through Hydroformylation
Neibecker, Denis,Reau, Regis,Lecolier, Serge
, p. 5208 - 5210 (1989)
The rhodium-phospholes and rhodium-phosphanorbornadienes-catalyzed hydroformylation of the readily available vinylarenes 1-3 gives rise to arylpropionaldehydes 4-6 in good yields.
Selective Transfer Semihydrogenation of Alkynes with H2O (D2O) as the H (D) Source over a Pd-P Cathode
Liu, Cuibo,Lu, Siyu,Wang, Changhong,Wu, Yongmeng,Zhang, Bin
supporting information, p. 21170 - 21175 (2020/09/11)
We reported a selective semihydrogenation (deuteration) of numerous terminal and internal alkynes using H2O (D2O) as the H (D) source over a Pd-P alloy cathode at a lower potential. P-doping caused the enhanced specific adsorption of alkynes and the promoted intrinsic activity for producing adsorbed atomic hydrogen (H*ads) from water electrolysis. The semihydrogenation of alkynes could be accomplished at a lower potential with up to 99 % selectivity and 78 % Faraday efficiency of alkene products, outperforming pure Pd and commercial Pd/C. This electrochemical semihydrogenation of alkynes might proceed via a H*ads addition pathway rather than a proton-coupled electron transfer process. The decreased amount of H*ads at a lower potential and the more preferential adsorption of the Pd-P to C≡C π bond than C=C moiety resulted in the excellent alkene selectivity. This method was capable of producing mono-, di-, and tri-deuterated alkenes with up to 99 % deuterium incorporation.
Catalytic Asymmetric Dearomatization by Visible-Light-Activated [2+2] Photocycloaddition
Hu, Naifu,Jung, Hoimin,Zheng, Yu,Lee, Juhyeong,Zhang, Lilu,Ullah, Zakir,Xie, Xiulan,Harms, Klaus,Baik, Mu-Hyun,Meggers, Eric
supporting information, p. 6242 - 6246 (2018/05/03)
A novel method for the catalytic asymmetric dearomatization by visible-light-activated [2+2] photocycloaddition with benzofurans and one example of a benzothiophene is reported, thereby providing chiral tricyclic structures with up to four stereocenters including quaternary stereocenters. The benzofurans and the benzothiophene are functionalized at the 2-position with a chelating N-acylpyrazole moiety which permits the coordination of a visible-light-activatable chiral-at-rhodium Lewis acid catalyst. Computational molecular modeling revealed the origin of the unusual regioselectivity and identified the heteroatom in the heterocycle to be key for the regiocontrol.
