80379-89-1

Basic information

• Product Name: Benzene, 1-(1-chloroethyl)-3-phenoxy-
• CAS NO: 80379-89-1
• Molecular Formula: C14H13ClO
• Molecular Weight: 232.71
• Mol File: 80379-89-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(1-chloroethyl)-3-phenoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(1-chloroethyl)-3-phenoxy-(80379-89-1)
• EPA Substance Registry System: Benzene, 1-(1-chloroethyl)-3-phenoxy-(80379-89-1)

Safety Data

• Hazardous Substances Data: 80379-89-1(Hazardous Substances Data)

Upstream product

• 39515-51-0 3-Phenoxybenzaldehyde 
• 32852-93-0 (RS)-1-(3-phenoxyphenyl)ethanol 

Downstream Products

• 63444-54-2 3-ethenylphenyl phenyl ether 
• 122801-83-6 3-(3-phenoxyphenyl)propanal 
• 59908-87-1 2-(3-phenoxy-phenyl)-propionaldehyde 
• 108671-27-8 3-(3-Phenoxy-phenyl)-butan-2-one 
• 29679-58-1 Fenoprofen 

Relevant articles and documents

Nickel-Catalyzed Stereo- and Enantioselective Cross-Coupling of gem-Difluoroalkenes with Carbon Electrophiles by C?F Bond Activation

Stereo- and enantioselective cross-electrophile coupling involving C?F bond activation is reported. Treatment of gem-difluoroalkenes with racemic benzyl electrophiles in the presence of a chiral nickel complex using B2pin2 as a stoichiometric reductant allows the construction of a C(sp2)?C(sp3) bond under mild conditions, affording a broad range of monofluoroalkenes bearing stereogenic allylic centers. Initial mechanistic studies indicate that a radical chain pathway may be operating, wherein the ester group in the gem-difluoroalkene promotes C?F bond activation through oxidative addition to a Ni species.