63759-94-4Relevant articles and documents
Microwave assisted solid phase synthesis of highly functionalized N-alkylated oligobenzamide α-helix mimetics
Long, Kérya,Edwards, Thomas A.,Wilson, Andrew J.
, p. 4034 - 4040 (2013/07/27)
Protein-protein interactions (PPIs) mediate cellular pathways and are implicated in numerous aberrant conditions. α-Helix mimetics - small molecules that reproduce the spatial projection of key residues from an α-helix involved in a PPI - are attractive generic templates for development of screening libraries, however library syntheses of α-helix mimetics with diverse functionality are less established. This manuscript describes the automated, microwave assisted solid phase synthesis based on one such scaffold; an N-alkylated oligobenzamide.
Hypolipidaemic compounds and compositions
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, (2008/06/13)
Certain substituted aralkylanilines in which the aromatic aniline ring carries, at the para position to the amino function, a substituent which comprises a carboxylic acid, salt or ester, an alkyl, hydroxyalkyl, cyano or acyl group, have hypolipidaemic ac
