638169-42-3Relevant articles and documents
Novel Extension of Meyers' Methodology: Stereoselective Construction of Axially Chiral 7,5-Fused Bicyclic Lactams
Penhoat, Mael,Levacher, Vincent,Dupas, Georges
, p. 9517 - 9520 (2007/10/03)
A novel extension of Meyer's lactamization is reported for the preparation of seven-membered ring lactams 1a-d incorporating a biaryl unit. The required keto-esters 2a-c were readily accessible via the Suzuki coupling reaction. A borylation-Suzuki couplin