652970-36-0

Basic information

• Product Name: L-Proline, 1-benzoyl-4-(phenylseleno)-, methyl ester, (4S)-
• CAS NO: 652970-36-0
• Molecular Formula: C19H19NO3Se
• Molecular Weight: 388.325
• Mol File: 652970-36-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Proline, 1-benzoyl-4-(phenylseleno)-, methyl ester, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Proline, 1-benzoyl-4-(phenylseleno)-, methyl ester, (4S)-(652970-36-0)
• EPA Substance Registry System: L-Proline, 1-benzoyl-4-(phenylseleno)-, methyl ester, (4S)-(652970-36-0)

Safety Data

• Hazardous Substances Data: 652970-36-0(Hazardous Substances Data)

Upstream product

• 51-35-4 4R-4-hydroxyproline 
• 31560-20-0 (2S,4R)-1-benzoyl-4-hydroxypyrrolidine-2-carboxylic acid methyl ester 
• 1499-56-5 (R)-4-hydroxy-L-proline ethyl ester 
• 1666-13-3 diphenyl diselenide 
• 31560-21-1 methyl (2S,4R)-1-benzoyl-4-(p-toluenesulfonyloxy)pyrrolidine-2-carboxylate 

Downstream Products

• 652970-42-8 (2S,4S)-(1-benzoyl-4-phenylselenopyrrolidin-2-yl)methyl benzoate 
• 652970-44-0 (1R,2S,3S,6R,7S)-(4-benzoyl-4-azatricyclo[5.2.1.0^2,6]dec-8-en-3-yl)methyl benzoate 
• 652970-37-1 methyl (1R,2S,3S,6R,7S)-4-benzoyl-4-azatricyclo[5.2.1.0^2,6]dec-8-ene-3-carboxylate 
• 652970-43-9 (2S)-(1-benzoyl-3-pyrrolin-2-yl)methyl benzoate 
• 5493-38-9 N-benzoyl-L-proline methyl ester 
• 56439-58-8 N,O-Dibenzoyl-L-prolinol 
• 648934-62-7 methyl (2S)-1-benzoylpyrrolidin-3-ene-2-carboxylate 

Relevant articles and documents

Synthetic study of optically active 3-azabicyclo[3.3.0]octane-2,6,8- tricarboxylic acid

Synthesis of (1R,2S,5S,6R,8S)-3-azabicyclo[3.3.0]octane-2,6,8-tricarboxylic acid (2) from trans-4-hydroxy-L-proline (5) was attempted. A Diels-Alder reaction of 3,4-dehydroproline derivative 9 and cyclopentadiene afforded a single stereoisomer 11. The Diels-Alder adduct was smoothly converted to the hydrochloride of 2 (24) via RuO4 oxidation. Although some racemization of the material or product was observed during the synthetic processes, the amino acid 24 proved to be optically pure.