65359-99-1 Usage
General Description
ETHOXYHYDROXYPHOSPHINYLACETIC ACID is a chemical compound also known as glyphosate, which is an herbicide and crop desiccant used to kill weeds, especially annual broadleaf weeds and grasses that compete with crops. It works by inhibiting a specific enzyme that is necessary for plant growth, ultimately leading to the death of the targeted plants. Glyphosate has been widely used in agriculture, forestry, and urban landscaping, but its use has been the subject of controversy due to its potential negative impact on human health and the environment. Studies have suggested a possible link between glyphosate exposure and various health risks, including cancer and reproductive issues, leading to some jurisdictions banning or restricting its use.
Check Digit Verification of cas no
The CAS Registry Mumber 65359-99-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,3,5 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 65359-99:
(7*6)+(6*5)+(5*3)+(4*5)+(3*9)+(2*9)+(1*9)=161
161 % 10 = 1
So 65359-99-1 is a valid CAS Registry Number.
InChI:InChI=1/C4H9O5P/c1-2-9-10(7,8)3-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)
65359-99-1Relevant articles and documents
Intramolecular monodealkylation during the attempted synthesis of diethylphosphonoacetohydroxamic acid
Chen, Ravit,Breuer, Eli
, p. 67 - 71 (2007/10/03)
The reaction of diethyl methyl phosphonoacetate (1) with hydroxylamine in NaOH solution resulted in the loss of one of the phosphorus ethyl groups, and yielded monoethylphosphonoaceto-hydroxamic acid (2) as the major product (79%) and diethylphosphonoacetic acid (3) as the minor product (21%). A series of control experiments were carried out to elucidate the sequence of the reactions leading to 2. When the reaction of 1 with NH2OH was carried out in NaHCO3 solution, a transient product 4 was also observed, which slowly transformed to 2. Compound 4 was assigned the structure diethylphos-phonoacetohydroxamic acid. There was no dealkylation observed at the phosphorus when 1 was reacted with methoxylamine or when O-methyl diethylphosphonoacetohydroxamate (7) was placed in alkaline solution. The dealkylation at phosphorus was interpreted in terms of intramolecular nucleophilic catalysis by the hydroxamic OH group attacking the phosphorus in 4, involving cyclic 1, 2,5-oxazaphospholidine intermediates.
