65865-28-3 Usage
Description
[5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL, also known as 5-TFMF, is a chemical compound characterized by its molecular formula C7H5F3O2. It is a colorless liquid at room temperature, featuring a furanyl group and a trifluoromethyl group. These functional groups make it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Its versatility in chemical reactions and potential biological activities, including anti-inflammatory and anti-cancer properties, highlight its importance in the field of organic synthesis.
Uses
Used in Pharmaceutical Synthesis:
[5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL is used as a building block for the synthesis of pharmaceuticals, leveraging its furanyl and trifluoromethyl groups to introduce these functional groups into target molecules, which can enhance the pharmacological properties of the resulting compounds.
Used in Agrochemical Production:
In the agrochemical industry, [5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL is utilized as a key intermediate in the synthesis of various agrochemicals, contributing to the development of effective and targeted pest control solutions.
Used as a Solvent in Organic Synthesis:
[5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL serves as a solvent in organic synthesis, facilitating a range of chemical reactions due to its unique properties as a colorless liquid at room temperature.
Used in the Production of Other Organic Compounds:
As an intermediate, [5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL is used in the production of other organic compounds, expanding its applications across various chemical industries.
Used in Biological Research:
[5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL is studied for its potential biological activities, particularly as an anti-inflammatory and anti-cancer agent, indicating its possible use in the development of new therapeutic agents.
However, due to the limited understanding of its toxicological properties, caution is advised when handling and using [5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL to ensure safety in research and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 65865-28-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,8,6 and 5 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 65865-28:
(7*6)+(6*5)+(5*8)+(4*6)+(3*5)+(2*2)+(1*8)=163
163 % 10 = 3
So 65865-28-3 is a valid CAS Registry Number.
65865-28-3Relevant articles and documents
Grigorash et al.
, (1977)
THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS
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Page 245, (2008/06/13)
Disclosed are novel compounds of the formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, acute pain, acute and chronic inflammatory pain, and neuropathic pain using a compound of formula (IA).
3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
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Page 126, (2008/06/13)
There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.
