66384-45-0

Basic information

• Product Name: N-[2-(2-iodo-4,5-dimethoxyphenyl)ethyl]acetamide
• Synonyms: N-[2-(2-iodo-4,5-dimethoxyphenyl)ethyl]acetamide
• CAS NO: 66384-45-0
• Molecular Formula: C₁₂H₁₆INO₃
• Molecular Weight: 349.16481
• Mol File: 66384-45-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-[2-(2-iodo-4,5-dimethoxyphenyl)ethyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(2-iodo-4,5-dimethoxyphenyl)ethyl]acetamide(66384-45-0)
• EPA Substance Registry System: N-[2-(2-iodo-4,5-dimethoxyphenyl)ethyl]acetamide(66384-45-0)

Safety Data

• Hazardous Substances Data: 66384-45-0(Hazardous Substances Data)

Upstream product

• 174533-44-9 N,N-dibenzoyl-N-2-(3,4-dimethoxyphenyl)ethylamine 
• 147820-02-8 N,N-diacetyl-N-2-(3,4-dimethoxyphenyl)ethylamine 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 67616-16-4 N-[2-(3,4-dimethoxyphenyl)ethyl]benzamide 
• 6275-29-2 N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide 

Downstream Products

• 138937-28-7 5,6-dihydroxyindoline hydrobromide 
• 29539-03-5 5,6-dihydroxy-indoline 
• 203806-39-7 N-(tert-butoxycarbonyl)-2-(4,5-dimethoxy-2-vinylphenyl)ethylamine 
• 1384186-21-3 (2S,3R)-3-((tert-butyldimethylsilyl)oxy)-N-(4,5-dimethoxy-2-vinylphenethyl)-2-isobutylpent-4-enamide 
• 1384186-18-8 2-(4,5-dimethoxy-2-vinylphenyl)ethanamine 
• 1314098-76-4 N-(tert-butoxycarbonyl)-2-(2-iodo-4,5-dimethoxyphenyl)ethylamine 
• 1228458-10-3 (2R,3S,11bR)-2-hydroxy-3-isobutyl-9,10-dimethoxy-2,3,6,7-tetrahydro-1H-pyrido[2,1-α]isoquinolin-4(11bH)-one 
• 1384186-29-1 C₄₀H₅₈N₂O₈ 
• 1228458-05-6 (5S,6R,E)-6-(tert-butyldimethylsilyloxy)-5-isobutyl-10,11-dimethoxy-2,3,5,6-tetrahydrobenzo[d]azecin-4(1H)-one 
• 1384186-23-5 C₅₂H₈₆N₂O₈Si₂ 
• 1026016-83-0 ((3R,11bR)-3-isobutyl-9.10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one) 
• 1384186-28-0 N-2-(2-iodo-4,5-dimethoxyphenyl)ethyl-tert-butoxycarbonylacetamide 
• 15937-10-7 1-acetyl-2,3-dihydro-5,6-dimethoxy-1H-indole 
• 1268372-68-4 (E)-N-(2-(3-hydroxyprop-1-enyl)-4,5-dimethoxyphenethyl)acetamide 

Relevant articles and documents

Preparation method of compound 5,6-dihydroxy indoline and halogen acid salts thereof

The invention relates to a preparation method of a compound 5,6-dihydroxy indoline and halogen acid salts thereof. Phenylethylamine SM-0 sold in the market is used as a raw material and firstly reactswith acyl chloride to obtain amide SM-1; amide SM-1 rea

A ring-closing metathesis-based approach to the synthesis of (+)-tetrabenazine

A modular stereoselective synthesis of the vesicular monoamine transport inhibitors (+)-tetrabenazine ((+)-1) and (+)-α-dihydrotetrabenazine ((+)-2) has been developed. The approach is based on amine 4 and acid 5 as the key building blocks, which were elaborated into macrolactam 3 by amide coupling and a subsequent highly E-selective RCM reaction. Macrolactam 3 could be converted into tetrabenazine in three known steps.

Application of the ortho-Lithiation-Cyclization Strategy to N-Benzyl- and N-Phenethylamine Derivatives

The ortho-lithiation-cyclization of iodinated N,N-diacylphenethylamines provides a convenient method for the preparation of 2-(2-acetoamidoethyl)acetophenones and 2-(2-benzamidoethyl)benzophenones, which could be easily transformed into dihydroisoquinolines.By contrast, the N-ethylamino, N-acetylamino, and N-trimethylsilylamino moieties studied as ortho-directing groups provide poor assistance to the metalation of N-benzyl- and N-phenyethylamines and the corresponding isoindolone or isoquinolone derivatives are obtained in low yields.