66386-42-3

Basic information

• Product Name: N⁶,N⁶-bis(phenoxycarbonyl)-2',3',5'-O-triacetyladenosine
• Synonyms: N⁶,N⁶-bis(phenoxycarbonyl)-2',3',5'-O-triacetyladenosine
• CAS NO: 66386-42-3
• Molecular Weight: 633.571
• Mol File: 66386-42-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N⁶,N⁶-bis(phenoxycarbonyl)-2',3',5'-O-triacetyladenosine(CAS DataBase Reference)
• NIST Chemistry Reference: N⁶,N⁶-bis(phenoxycarbonyl)-2',3',5'-O-triacetyladenosine(66386-42-3)
• EPA Substance Registry System: N⁶,N⁶-bis(phenoxycarbonyl)-2',3',5'-O-triacetyladenosine(66386-42-3)

Safety Data

• Hazardous Substances Data: 66386-42-3(Hazardous Substances Data)

Upstream product

• 1885-14-9 phenyl chloroformate 
• 7387-57-7 triacetyladenosine 

Downstream Products

• 101077-81-0 9-(2-chloroethyl)-7,8-dihydro-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-3H-imidazo<4',5':4,5>-pyrimido<1,6-a><1,3,5>triazepine-10(9H)-one 
• 15180-53-7 4,4'-(carbonyldiimino)bis(2,2,6,6-tetramethylpiperidinyl-1-oxy) 
• 82838-87-7 4-<(phenoxycarbonyl)amino>-2,2,6,6-tetramethylpiperidinyl-1-oxy 
• 82838-86-6 2,2,6,6-tetramethyl-4-<<<<9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purin-6-yl>amino>carbonyl>amino>piperidinyl-1-oxy 

Relevant articles and documents

Reactions of Ethyl and Phenyl Chloroformate with Adenosine Derivatives as an Entry to N6-Ureido-Linked Spin-Labeled Adenosine and Other Modified Adenosines

2',3',5'-O-Triacetyl-N6,N6-bis(phenoxycarbonyl)adenosine (10) reacted readlly with 4-amino-2,2,6,6-tetramethylpiperidinyl-1-oxy to afford an 87percent yield of ureido compound 16, which was then deacetylated to give spin-labeled adenosine derivative 19 in 56percent yield.Adenosine derivatives 24-27 were prepared from 10 in a similar manner.Treatment of 2',3'-O-isopropylideneadenosine (2) with phenyl chloroformate gave O5',8-cycloadenosines 13 and 14; structure 13 was assigned on the basis of long-range selective proton-decoupled (LSPD) 13C NMR spectra.O5',8-Cycloadenosine 8 was similarly prepared from 2 and ethyl chloroformate.Reaction of 2',3',5'-O-triacetyladenosine (9) with phenyl chloroformate in the presence of dimethylformamide afforded amidine derivative 12 (74percent).