82838-86-6

Basic information

• Product Name: 2,2,6,6-tetramethyl-4-<<<<9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purin-6-yl>amino>carbonyl>amino>piperidinyl-1-oxy
• CAS NO: 82838-86-6
• Molecular Weight: 590.613
• Mol File: 82838-86-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2,6,6-tetramethyl-4-<<<<9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purin-6-yl>amino>carbonyl>amino>piperidinyl-1-oxy(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,6,6-tetramethyl-4-<<<<9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purin-6-yl>amino>carbonyl>amino>piperidinyl-1-oxy(82838-86-6)
• EPA Substance Registry System: 2,2,6,6-tetramethyl-4-<<<<9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purin-6-yl>amino>carbonyl>amino>piperidinyl-1-oxy(82838-86-6)

Safety Data

• Hazardous Substances Data: 82838-86-6(Hazardous Substances Data)

Upstream product

• 66386-42-3 N⁶,N⁶-bis(phenoxycarbonyl)-2',3',5'-O-triacetyladenosine 
• 14691-88-4 4-amino-2,2,6,6-tetramethyl-1-piperidine-1-oxyl 

Relevant articles and documents

Reactions of Ethyl and Phenyl Chloroformate with Adenosine Derivatives as an Entry to N6-Ureido-Linked Spin-Labeled Adenosine and Other Modified Adenosines

2',3',5'-O-Triacetyl-N6,N6-bis(phenoxycarbonyl)adenosine (10) reacted readlly with 4-amino-2,2,6,6-tetramethylpiperidinyl-1-oxy to afford an 87percent yield of ureido compound 16, which was then deacetylated to give spin-labeled adenosine derivative 19 in 56percent yield.Adenosine derivatives 24-27 were prepared from 10 in a similar manner.Treatment of 2',3'-O-isopropylideneadenosine (2) with phenyl chloroformate gave O5',8-cycloadenosines 13 and 14; structure 13 was assigned on the basis of long-range selective proton-decoupled (LSPD) 13C NMR spectra.O5',8-Cycloadenosine 8 was similarly prepared from 2 and ethyl chloroformate.Reaction of 2',3',5'-O-triacetyladenosine (9) with phenyl chloroformate in the presence of dimethylformamide afforded amidine derivative 12 (74percent).