664364-60-7

Basic information

• Product Name: N-Cbz-3-Methylnipecotic acid ethyl ester
• Synonyms: 3-Methyl-1,3-piperidinedicarboxylic acid 3-ethyl 1-(phenylmethyl) ester;N-Cbz-3-Methylnipecotic acid ethyl ester;Ethyl 1-Cbz-3-Methylpiperidine-3-carboxylate;1-benzyl 3-ethyl 3-methylpiperidine-1,3-dicarboxylate;1-O-benzyl 3-O-ethyl 3-methylpiperidine-1,3-dicarboxylate
• CAS NO: 664364-60-7
• Molecular Formula: C₁₇H₂₃NO₄
• Molecular Weight: 305.37
• Mol File: 664364-60-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.137
• Refractive Index: 1.525
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-Cbz-3-Methylnipecotic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Cbz-3-Methylnipecotic acid ethyl ester(664364-60-7)
• EPA Substance Registry System: N-Cbz-3-Methylnipecotic acid ethyl ester(664364-60-7)

Safety Data

• Hazardous Substances Data: 664364-60-7(Hazardous Substances Data)

Usage

General Description

N-Cbz-3-Methylnipecotic acid ethyl ester is a chemical compound used primarily in scientific research. The term “N-Cbz” refers to the carboxybenzyl protection group attached to the compound, which is commonly used in peptide synthesis. The "3-Methylnipecotic acid" part indicates the presence of a nipecotic acid derivative, which is of interest due to nipecotic acid's role as an inhibitor of gamma-aminobutyric acid (GABA) uptake. The addition of "ethyl ester" implies an ester functional group, which enhances the compound's solubility and allows for more efficient chemical reactions. N-Cbz-3-Methylnipecotic acid ethyl ester is typically prepared in a laboratory setting and is not naturally occurring.

InChI:InChI=1/C17H23NO4/c1-3-21-15(19)17(2)10-7-11-18(13-17)16(20)22-12-14-8-5-4-6-9-14/h4-6,8-9H,3,7,10-13H2,1-2H3

Upstream product

• 310454-53-6 3-ethyl 1-(phenylmethyl) 1,3-piperidinedicarboxylate 
• 74-88-4 methyl iodide 
• 71962-74-8 Ethyl nipecotate 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 169750-96-3 tert-butyl N-(3-methyl-3-piperidinyl)carbamate 
• 1196506-86-1 rac-benzyl 3-((tert-butoxycarbonyl)amino)-3-methylpiperidine-1-carboxylate 
• 174543-78-3 1-((benzyloxy)carbonyl)-3-methylpiperidine-3-carboxylic acid 
• 170843-43-3 3-methylpiperidine-3-carboxylic acid ethyl ester 

Relevant articles and documents

DIAMINOCYCLOHEXANE COMPOUNDS AND USES THEREOF

The present invention provides compounds of Formula (I) or a stereo isomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are agonists, partial agonists and modulators of the NPY Y4 rece

Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme

The present invention relates to compounds that are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.