67052-53-3

Basic information

• Product Name: Ethanone, 1-[2-(methoxymethoxy)-4,6-bis(phenylmethoxy)phenyl]-
• CAS NO: 67052-53-3
• Molecular Formula: C24H24O5
• Molecular Weight: 392.452
• Mol File: 67052-53-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[2-(methoxymethoxy)-4,6-bis(phenylmethoxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[2-(methoxymethoxy)-4,6-bis(phenylmethoxy)phenyl]-(67052-53-3)
• EPA Substance Registry System: Ethanone, 1-[2-(methoxymethoxy)-4,6-bis(phenylmethoxy)phenyl]-(67052-53-3)

Safety Data

• Hazardous Substances Data: 67052-53-3(Hazardous Substances Data)

Upstream product

• 18065-05-9 1-[2,4-bis(benzyloxy)-6-hydroxyphenyl]ethanone 
• 107-30-2 chloromethyl methyl ether 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 115-10-6 Dimethyl ether 
• 100-39-0 benzyl bromide 

Downstream Products

• 71386-98-6 2',4'-dihydroxy-6'-(methoxymethoxy)acetophenone 
• 896121-49-6 racemic 5,7,3',4'-tetra-O-benzyl-(+/-)-catechin 
• 154-23-4 catechin 
• 211255-69-5 5,7,3'-trihydroxydihydroquercetin 3-acetate 4'-(methyl ether) 
• 369371-89-1 acetic acid 3,5-bis-benzyloxy-2-[2-(2,4-bis-benzyloxy-5-methoxy-phenyl)-3,3-dimethoxy-propionyl]-phenyl ester 
• 369371-86-8 acetic acid 3,5-bis-benzyloxy-2-[2-(2,4-bis-benzyloxy-phenyl)-3,3-dimethoxy-propionyl]-phenyl ester 
• 369371-85-7 Acetic acid 3,5-bis-benzyloxy-2-[(E)-3-(2,4-bis-benzyloxy-phenyl)-acryloyl]-phenyl ester 
• 120980-05-4 (E)-1-(2,4-Bis-benzyloxy-6-hydroxy-phenyl)-3-(2,4-bis-benzyloxy-phenyl)-propenone 
• 82458-45-5 2',4',5,7-tetrakis(benzyloxy)isoflavone 
• 98094-87-2 Lupinalbin A 
• 1156-78-1 2',4',5,7-tetrahydroxyisoflavone 
• 67978-82-9 Acetic acid 3,5-bis-benzyloxy-2-[(E)-3-(2,4-bis-benzyloxy-5-methoxy-phenyl)-acryloyl]-phenyl ester 
• 67978-84-1 5,7-bis-benzyloxy-3-(2,4-bis-benzyloxy-5-methoxy-phenyl)-chromen-4-one 
• 67978-85-2 Piscerygenin 

Relevant articles and documents

A catechin preparation method of compound (by machine translation)

The invention relates to a method for preparing a catechin compound. The method comprises the following steps: by taking 2,4,6-trihydroxy acetophenone and p-hydroxy benzaldehyde as raw materials, carrying out condensation reaction, restored deoxidation, cyclization reaction of acid catalysis, so as to obtain the catechin compound. The invention also provides a technology for producing the catechin compound. In the synthesis process of an immediate 9, reduction is carried out by using sodium borohydride which is catalyzed by a lewis acid, so that side reaction caused by double bond transfer is greatly reduced while a highly toxic reagent osmium tetroxide is replaced with hydrogen peroxide oxidation.

Regioselective synthesis of prenylisoflavones. Syntheses of allolicoisoflavone A, 2,3-dehydrokievitone, and related compounds

The palladium-catalyzed coupling reaction of 2',4',5,7- tetrakis(benzyloxy)-5'-iodolsoflavone (12), synthesized from the 5- iodochalcone 9, with 2-methyl-3-butyn-2-ol gave the corresponding 5'-(3- hydroxy-3-methyl-1-butynyl)isoflavone 13. The catalytic hydrogenation of 13 gave 2',4',5,7-tetrahydroxy-5'-(3-hydroxy-3-methylbutyl)isoflavone (2). Dehydration of the benzoate 14 of 2 afforded a mixture of 5'-(3-methyl-2- butenyl)isoflavone 15 and the isomer 5'-(3-methyl-3-butenyl)isoflavone 16. The separation of 15 was accomplished by a treatment of the mixture (15 and 16) with mercury(II) nitrate. Hydrolysis of 15 afforded 2',4',5,7- tetrahydroxy-5'-prenylisoflavone (allolicoisoflavone A) (1). In a similar manner, 2',4',5,7-tetrahydroxy-8-prenylisoflavone (2,3-dehydrokievitone) (3) and 2',4',5,7-tetrahydroxy-8-(3-hydroxy-3-methylbutyl)isoflavone (2,3- dehydrokievitone hydrate) (4) were synthesized from the corresponding 8- iodoisoflavone 22. The tetramethyl ether 5 of 3 was also prepared from the 8- iodotetramethoxyisoflavone 32.