67157-60-2

Basic information

• Product Name: Benzoic acid, 2-methyl-, phenylmethyl ester
• CAS NO: 67157-60-2
• Molecular Formula: C15H14O2
• Molecular Weight: 226.275
• Mol File: 67157-60-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-methyl-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-methyl-, phenylmethyl ester(67157-60-2)
• EPA Substance Registry System: Benzoic acid, 2-methyl-, phenylmethyl ester(67157-60-2)

Safety Data

• Hazardous Substances Data: 67157-60-2(Hazardous Substances Data)

Upstream product

• 39627-62-8 1-(o-tolyl)-2-propen-1-ol 
• 108-88-3 toluene 
• 95-46-5 2-methylphenyl bromide 
• 104-57-4 benzyl formate 
• 89-71-4 2-Methyl-benzoic acid methyl ester 
• 100-51-6 benzyl alcohol 
• 89-95-2 2-methyl-benzyl alcohol 
• 529-20-4 2-methylphenyl aldehyde 
• 703-59-3 homophthalic anhydride 
• 908094-04-2 phenyldiazomethane 
• 70063-30-8 o-Carboxyphenylperessigsaeure-tert.-butylester 
• 100-44-7 benzyl chloride 
• 3469-06-5 benzocyclobutenone 
• 118-90-1 ortho-methylbenzoic acid 

Downstream Products

• 118-90-1 ortho-methylbenzoic acid 
• 620-83-7 1-methyl-4-(phenylmethyl)benzene 
• 713-36-0 2-benzyltoluene 
• 108-88-3 toluene 
• 100-51-6 benzyl alcohol 

Relevant articles and documents

Bu 4 NI-Catalyzed C-C Bond Cleavage and Oxidative Esteri??cation of Allyl Alcohols with Toluene Derivatives

A novel oxidative esterification of 1-arylprop-2-en-1-ols with toluene derivatives catalyzed by tetrabutylammonium iodide (TBAI) is reported. The optimization of the reaction conditions illustrates that each of experiment parameters including the catalyst, solvent, and oxidant is significant for present oxidative functionalization. This metal-free protocol has a broad substrate scope including the halogen groups for further functionalization and enriches the reactivity profile of allyl alcohol and toluene derivatives. In addition, this protocol represents a new transformation of allyl alcohol involving C-C bond cleavage and C-O bond forming.

METHOD OF CONVERTING ALCOHOL TO HALIDE

The present invention relates to a method of converting an alcohol into a corresponding halide. This method comprises reacting the alcohol with an optionally substituted aromatic carboxylic acid halide in presence of an N-substituted formamide to replace a hydroxyl group of the alcohol by a halogen atom. The present invention also relates to a method of converting an alcohol into a corresponding substitution product. The second method comprises: (a) performing the method of the invention of converting an alcohol into the corresponding halide; and (b) reacting the corresponding halide with a nucleophile to convert the halide into the nucleophilic substitution product.

Transition metal free oxidative esterification of alcohols with toluene

Using Bu4NI as the catalyst and tert-butyl hydroperoxide as the oxidant, direct esterification of alcohols with toluene derivatives was achieved. Mechanistic investigations indicate that the alcohols are sequentially oxidized to aldehydes, carboxylic acids, and then to benzyl esters. Bu 4N+ functions as a phasetransfer reagent and iodide catalyzes the reaction.