676129-92-3

Basic information

• Product Name: S)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)aMino)-3- Methylbutanoic acid
• Synonyms: S)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)aMino)-3- Methylbutanoic acid
• CAS NO: 676129-92-3
• Molecular Formula: C₁₉H₂₁N₅O₂
• Molecular Weight: 351.40234
• EINECS: -0
• Mol File: 676129-92-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 598.2±60.0 °C(Predicted)
• Appearance: /
• Density: 1.250±0.06 g/cm3(Predicted)
• PKA: 2.29±0.13(Predicted)
• CAS DataBase Reference: S)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)aMino)-3- Methylbutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: S)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)aMino)-3- Methylbutanoic acid(676129-92-3)
• EPA Substance Registry System: S)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)aMino)-3- Methylbutanoic acid(676129-92-3)

Safety Data

• Hazardous Substances Data: 676129-92-3(Hazardous Substances Data)

Usage

General Description

S)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)aMino)-3- Methylbutanoic acid is a chemical compound that is a ligand for angiotensin II type 1 (AT1) receptor. It is commonly used as an antihypertensive agent to treat high blood pressure, congestive heart failure, and to improve survival after heart attack. S)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)aMino)-3- Methylbutanoic acid works by blocking the action of angiotensin, a natural substance in the body that raises blood pressure. It is typically administered orally and has been found to be effective in reducing blood pressure and improving cardiac function in patients with heart disease. However, it may also cause side effects such as dizziness, hypotension, and hyperkalemia.

Upstream product

• 137862-53-4 N-pentanoyl-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]-methyl]-(L)-valine 
• 482577-59-3 N-((2'-cyano[1,1'-biphenyl]-4-yl)methyl)-L-valine methyl ester hydrochloride 
• 676129-91-2 3-methyl-2{[1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl]-meth-(E/Z)-ylidene]-amino}-butyric acid 
• 72-18-4 L-valine 
• 151052-40-3 2'-(1H-tetrazol-5-yl)biphenyl-4-carbaldehyde 
• 133292-05-4 4-(diethoxymethyl)phenylmagnesium bromide 
• 34421-94-8 4-bromobenzaldehyde diethyl acetal 
• 73096-42-1 5-(2-bromophenyl)-1H-tetrazole 
• 676130-06-6 5-(4'-diethoxymethyl-biphenyl-2-yl)-2-(tetrahydro-pyran-2-yl)-2H-tetrazole 
• 676130-02-2 5-(2-bromophenyl)-2-(tetrahydropyran-2-yl)-2H-tetrazole 

Downstream Products

• 2254485-68-0 C₁₉H₂₀N₆O₃ 
• 137862-53-4 N-pentanoyl-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]-methyl]-(L)-valine 

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