67659-36-3 Usage
Description
(R)-1,1-DIPHENYL-2-AMINOPROPANE, also known as (R)-(+)-1,1-Diphenyl-2-aminopropane, is an organic compound with a chiral center, characterized by its unique molecular structure featuring two phenyl rings and an aminopropane chain. It is a versatile chemical intermediate with potential applications in various fields due to its distinct stereochemistry and reactivity.
Uses
Used in Pharmaceutical Industry:
(R)-1,1-DIPHENYL-2-AMINOPROPANE is used as a precursor for the preparation of trisubstituted dihydroisoquinoline derivatives via the Bischler-Napieralski reaction. This reaction is a key synthetic method for the formation of various bioactive compounds, including those with potential therapeutic applications. The chiral nature of (R)-1,1-DIPHENYL-2-AMINOPROPANE allows for the selective synthesis of enantiomerically pure products, which is crucial for the development of drugs with improved efficacy and reduced side effects.
Additionally, due to its structural features, (R)-1,1-DIPHENYL-2-AMINOPROPANE may also find use in other industries such as materials science for the development of novel polymers or in the synthesis of chiral ligands for asymmetric catalysis. However, the specific applications in these fields would require further research and development to fully explore the compound's potential.
Check Digit Verification of cas no
The CAS Registry Mumber 67659-36-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,6,5 and 9 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 67659-36:
(7*6)+(6*7)+(5*6)+(4*5)+(3*9)+(2*3)+(1*6)=173
173 % 10 = 3
So 67659-36-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H17N/c1-12(16)15(13-8-4-2-5-9-13)14-10-6-3-7-11-14/h2-12,15H,16H2,1H3/t12-/m1/s1
67659-36-3Relevant articles and documents
COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS
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Page/Page column 45-50, (2010/12/31)
The present invention relates to derivatized cyclofructan compounds, compositions comprising derivatized cyclofructan compounds, and methods of using compositions comprising derivatized cyclofructan compounds for chromatographic separations of chemical species, including enantiomers. Said compositions may comprise a solid support and/or polymers comprising derivatized cyclofructan compounds.
Reactions of amino alcohols in superacid: the direct observation of dicationic intermediates and their application in synthesis.
Klumpp,Aguirre,Sanchez Jr.,de Leon
, p. 2781 - 2784 (2007/10/03)
[reaction: see text]. The chemistry of amino alcohols has been studied in superacidic media, and these compounds have been found to ionize cleanly to the dication intermediates. Several dicationic species have been directly observed by low-temperature 13C NMR, including those from epinephrine (adrenaline) and synephrine. Amino alcohols react (70-99% yields) with C6H6 in triflic acid (CF3SO3H) by electrophilic aromatic substitution.
