67960-31-0

Basic information

• Product Name: 5-chloro-3-(2-fluorophenyl)-1H-indole
• Synonyms: 5-chloro-3-(2-fluorophenyl)-1H-indole
• CAS NO: 67960-31-0
• Molecular Weight: 245.684
• Mol File: 67960-31-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-chloro-3-(2-fluorophenyl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-3-(2-fluorophenyl)-1H-indole(67960-31-0)
• EPA Substance Registry System: 5-chloro-3-(2-fluorophenyl)-1H-indole(67960-31-0)

Safety Data

• Hazardous Substances Data: 67960-31-0(Hazardous Substances Data)

Upstream product

• 488828-89-3 4-chloro-2-(1-(2-fluorophenyl)vinyl)aniline 
• 784-38-3 2-amino-5-chloro-2'-fluorobenzophenone 
• 5922-60-1 2-amino-5-chlorobenzonitrile 
• 1993-03-9 o-fluorophenylboronic acid 

Relevant articles and documents

Iron-Promoted Construction of Indoles via Intramolecular Oxidative C-N Coupling of 2-Alkenylanilines Using Persulfate

Indole scaffold synthesis relies primarily on oxidative C-H amination of N-protected alkenylanilines for C-N intramolecular cyclization reactions. Herein, for the first time, without N-protection, various readily prepared 2-alkenylanilines were transformed into the desired indole products in good yields by using K 2 S 2 O 8 as oxidant in the presence of catalytic amounts of FeF 2. The K 2 S 2 O 8 /FeF 2 system offers a direct and benign synthetic route to 3-arylindoles and it is applicable to a wide range of substituted indoles including drug intermediates.