679839-07-7Relevant articles and documents
Hexafluoroisopropanol-Mediated Redox-Neutral α-C(sp3)-H Functionalization of Cyclic Amines via Hydride Transfer
Shen, Yao-Bin,Wang, Lin-Xuan,Sun, Yun-Ming,Dong, Feng-Ying,Yu, Liping,Liu, Qing,Xiao, Jian
, p. 1915 - 1926 (2020/02/04)
Hexafluoroisopropanol has been demonstrated as the versatile promoter for redox-neutral α-C(sp3)-H functionalization of cyclic amines via the cascade [1,5]-hydride transfer/cyclization strategy. A wide range of cyclic amines are functionalized
Method for synthetizing PNU-286607 and analogues of PNU-286607
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Paragraph 0041-0046; 0137, (2018/04/03)
The invention relates to a method for synthetizing PNU 286607 and analogues of PNU-286607. The method is concretely characterized in that 2-fluorine-5-nitrobenzaldehyde and secondary amine react underthe 20-80 DEG C water phase or ethyl alcohol phase cond
PYRIMIDOPYRIMIDINONES USEFUL AS WEE-1 KINASE INHIBITORS
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Paragraph 293; 294, (2015/07/07)
The present invention relates to compounds that are useful as inhibitors of the activity of Wee-1 kinase. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in the treatment of cancer and methods of treating cancer.