6850-35-7

Basic information

• Product Name: 3-METHYLCYCLOHEXYLAMINE
• Synonyms: 3-Methylcyclohexylamine (cis- and trans- mixture);1-Amino-3-methylcyclohexane;3-Methylcyclohexan-1-aMine;1,3-AMinoMethylcyclohexane;3-Methylcyclohexanamine;Cyclohexanamine, 3-methyl-;HEXAHYDRO-M-TOLUIDINE;3-METHYLCYCLOHEXYLAMINE
• CAS NO: 6850-35-7
• Molecular Formula: C₇H₁₅N
• Molecular Weight: 113.2
• EINECS: 229-940-1
• Product Categories: CMLLYL
• Mol File: 6850-35-7.mol
• Article Data: 10

Chemical Properties

• Melting Point: -8.5°C (estimate)
• Boiling Point: 151°C(lit.)
• Flash Point: 22 °C
• Appearance: /
• Density: 0.8550
• Vapor Pressure: 4.1mmHg at 25°C
• Refractive Index: 1.4510 to 1.4550
• PKA: 10.61±0.70(Predicted)
• CAS DataBase Reference: 3-METHYLCYCLOHEXYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYLCYCLOHEXYLAMINE(6850-35-7)
• EPA Substance Registry System: 3-METHYLCYCLOHEXYLAMINE(6850-35-7)

Safety Data

• Hazard Codes: F,C
• Statements: 10-22-34
• RIDADR: UN 2733 3/8/PG II
• HazardClass: IRRITANT
• PackingGroup: II
• Hazardous Substances Data: 6850-35-7(Hazardous Substances Data)

Usage

General Description

3-Methylcyclohexylamine is a chemical compound with the molecular formula C7H15N. It is a cycloalkylamine that is commonly used as an intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds. It is a clear, colorless liquid with a strong amine odor and is soluble in water and organic solvents. 3-Methylcyclohexylamine is also known for its use as a corrosion inhibitor in paints and coatings, as well as a stabilizer in polymers. It is considered to be a hazardous chemical and should be handled with care and appropriate safety measures.

InChI:InChI=1/C7H15N/c1-6-3-2-4-7(8)5-6/h6-7H,2-5,8H2,1H3

Upstream product

• 1193-18-6 3-methylcyclohexen-2-one 
• 540-69-2 ammonium formate 
• 108-44-1 1-amino-3-methylbenzene 
• 7647-01-0 hydrogenchloride 
• 64-19-7 acetic acid 
• 591-23-1 m-methylcyclohexanol 
• 7664-41-7 ammonia 
• 4701-95-5 3-methyl-cyclohexanone oxime 
• 591-24-2 3-Methylcyclohexanone 
• 99-08-1 1-methyl-3-nitrobenzene 
• 99-61-6 3-nitro-benzaldehyde 
• 127818-60-4 1-methyl-3-nitro-cyclohexane 
• 64-17-5 ethanol 

Downstream Products

• 92375-42-3 N-(3-methyl-cyclohexyl)-N'-phenyl-thiourea 
• 17485-49-3 C₁₅H₂₁N₃O₅S 
• 13908-14-0 1-(2-Chloro-ethyl)-3-(3-methyl-cyclohexyl)-urea 
• 15409-08-2 C₁₅H₂₃N₃O₃S 
• 108-44-1 1-amino-3-methylbenzene 
• 626-13-1 3,3'-ditolylamine 
• 1205-64-7 3-Methyldiphenylamine 

Relevant articles and documents

Synthesis of trans-3-substituted cyclohexylamines via Br?nsted acid catalyzed and substrate-mediated triple organocatalytic cascade reaction

We report a new organocatalytic cascade reaction. A combination of the amine substrate with a catalytic amount of a Br?nsted acid merges enamine and iminium catalysis with Br?nsted acid catalysis in a new organocatalytic cascade reaction. We found that the aniline substrate itself in combination with a catalytic amount of PTSA·H2O can function as an aminocatalyst accomplishing an aldol condensation-conjugate reduction cascade, which terminates in a Br?nsted acid catalyzed reductive amination incorporating the amine substrate into the final product. This transformation furnishes trans-3-substituted cyclohexyl amines in good yields and good diastereoselectivities. Georg Thieme Verlag Stuttgart.

Amino-Modified Silica-Supported Copper-Palladium Alloy. Synthesis and Use in Selective Hydrogenation of Disubstituted Nitroarenes in a Flow Micro Reactor

A copper-palladium catalyst supported on amino-modified silica has been synthesized by chemical reduction. It has been found that submicron particles of a copper-palladium alloy are formed on the silica surface. Unlike commercially available palladium catalysts (Pd/Al2O3, Pd/C, Pd/BaSO4), the synthesized copper-palladium catalyst makes it possible to selectively reduce the nitro group in 3-nitrobenzaldehyde and 1-chloro-4-nitrobenzene.

CATALYST COMPOUNDS

The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formulas: where ring B is either itself polycyclic, or ring B together with R is polycyclic. The catalysts of the invention are particularly effective in reductive amination procedures 10 which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions.