685141-81-5

Basic information

• Product Name: Phenylalanine, N-[2-[(benzo[b]thien-2-ylcarbonyl)amino]benzoyl]-, ethyl ester
• CAS NO: 685141-81-5
• Molecular Formula: C27H24N2O4S
• Molecular Weight: 472.565
• Mol File: 685141-81-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phenylalanine, N-[2-[(benzo[b]thien-2-ylcarbonyl)amino]benzoyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phenylalanine, N-[2-[(benzo[b]thien-2-ylcarbonyl)amino]benzoyl]-, ethyl ester(685141-81-5)
• EPA Substance Registry System: Phenylalanine, N-[2-[(benzo[b]thien-2-ylcarbonyl)amino]benzoyl]-, ethyl ester(685141-81-5)

Safety Data

• Hazardous Substances Data: 685141-81-5(Hazardous Substances Data)

Upstream product

• 3182-93-2 ethyl 2-amino-3-phenylpropanoate hydrochloride 
• 118-48-9 isatoic anhydride 
• 6314-28-9 benzo[b]thiophene-2-carboxylic acid 
• 39827-11-7 benzothiophene-2-carboxylic acid chloride 
• 32771-73-6 2(R,S)-(2-amino-benzoylamino)-3-phenyl-propionic acid ethyl ester 

Relevant articles and documents

Anthranilic acid based CCK1 antagonists: The 2-indole moiety may represent a "needle" according to the recent homonymous concept

Recently we described an innovative class of non-peptide CCK1 antagonists keeping appropriate pharmacophoric groups on the anthranilic acid employed as a molecular scaffold. The lead compound obtained, VL-0395, characterized by the presence of Phe and the 2-indole moiety at the C- and N-termini of anthranilic acid, respectively, is endowed with submicromolar affinity towards CCK1 receptors. Thus, we have prepared and tested on CCK receptors a library of VL-0395 analogues in order to investigate the precise topological and essential key interactions of the 2-indole group of the lead with the CCK1 receptor. The obtained results confirm that this group establishes very specific interactions with this receptor sub-site and may be viewed as a "needle" group.