68808-54-8

Basic information

• Product Name: 3-AMINO-1,4-DIMETHYL-5H-PYRIDO[4,3-B]INDOLE, ACETATE
• Synonyms: TRP-P-1 ACETATE;3-AMINO-1,4-DIMETHYL-5H-PYRIDO[4,3-B]INDOLE, ACETATE;3-b)indol-3-amine,1,4-dimethyl-5h-pyrido(acetate;3-b)indol-3-amine,1,4-dimethyl-5h-pyrido(monoacetate;3-b)indole,3-amino-1,4-dimethyl-5h-pyrido(acetate;1,4-Dimethyl-5H-pyrido[4,3-b]indol-3-amine Monoacetate;1,4-Dimethyl-5H-pyrido[4,3-β]indol-3-amine Monoacetate;3-Amino-1,4-dimethyl-5h-pyrido[4,3-β]indole, Acetate
• CAS NO: 68808-54-8
• Molecular Formula: C15H17N3O2
• Molecular Weight: 271.31
• Product Categories: Detergents;Mutagenesis Research Chemicals;Amines;Heterocycles
• Mol File: 68808-54-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 250-260
• Boiling Point: 460.2°C at 760 mmHg
• Flash Point: 263°C
• Appearance: /
• Vapor Pressure: 1.19E-08mmHg at 25°C
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly, Heated), Methanol (Slightly, Heated)
• CAS DataBase Reference: 3-AMINO-1,4-DIMETHYL-5H-PYRIDO[4,3-B]INDOLE, ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-1,4-DIMETHYL-5H-PYRIDO[4,3-B]INDOLE, ACETATE(68808-54-8)
• EPA Substance Registry System: 3-AMINO-1,4-DIMETHYL-5H-PYRIDO[4,3-B]INDOLE, ACETATE(68808-54-8)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45
• Hazardous Substances Data: 68808-54-8(Hazardous Substances Data)

Usage

Chemical Properties

Beige-Brown Crystalline Solid

Safety Profile

Suspected carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.

InChI:InChI=1/C13H13N3.C2H4O2/c1-7-12-11(8(2)15-13(7)14)9-5-3-4-6-10(9)16-12;1-2(3)4/h3-6,16H,1-2H3,(H2,14,15);1H3,(H,3,4)

Upstream product

• 69901-68-4 2-(1-cyanoethyl)-N-ethoxycarbonylindole 
• 17954-23-3 1-ethoxycarbonyl-1,2-dihydroquinoline-2-carbonitrile 
• 52618-53-8 2-(cyanomethyl)-N-ethoxycarbonylindole 
• 128257-19-2 methyl 3-<2-<3-<1-(hydroxyimino)ethyl>indolyl>>-2-butenoate 
• 143618-96-6 methyl 3-<2-(acetylindolyl)>-2-butenoate 
• 143618-89-7 methyl 3-(2-indolyl)-2-butenoate 
• 143618-93-3 3-(2-indolyl)-2-butenoic acid 
• 128257-21-6 5-<<2-<1-(benzenesulfonyl)indolyl>>ethylidene>-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 143618-91-1 (E)-3-(1-Benzenesulfonyl-1H-indol-2-yl)-but-2-enoic acid phenyl ester 
• 128257-25-0 methyl 1,4-dimethyl-5H-pyrido<4,3-b>indole-3-carboxylate 
• 96286-20-3 1,4-dimethyl-5H-pyrido<4,3-b>indole-3-carboxylic acid 
• 76017-87-3 2-(1H-indol-2-yl)propionitrile 
• 75-05-8 acetonitrile 
• 128257-26-1 t-Boc-Trp-P-1 

Relevant articles and documents

Synthesis of Genotoxic Heterocyclic Amines Trp-P-1 and Trp-P-2

Trp-P-1 (1a) and Trp-P-2 (1b) possessing a pyridoindole system have been newly synthesized.The key reaction step in the synthetic sequence has been the thermal electrocyclic reaction of the 1-azahexa-1,3,5-triene system 3 involving the indole bond derived from 2-vinylindoles 4. 2-Vinylindole 4a has been derived from N-(benzenesulfonyl)indole (5) in a four-step sequence. 2-Vinylindole 4b has been synthesized by two routes using either ethoxymethylidene Meldrum's acid (6b) or diethyl ethoxymethylidenemalonate (10) as Michael acceptors to the 2-lithio-N-(benzenesulfonyl)indole.