69032-13-9

Basic information

• Product Name: Bis(benzyloxycarbonyl)amine
• Synonyms: Bis(benzyloxycarbonyl)amine;Iminobis(formic acid benzyl) ester;N-[Benzyloxycarbonyl]carbamic acid benzyl ester;Dibenzyl iminodicarboxylate;Dibenzyl imidodicarboxylate
• CAS NO: 69032-13-9
• Molecular Formula: C₁₆H₁₅NO₄
• Molecular Weight: 285.2946
• Mol File: 69032-13-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 110.5-111℃
• Boiling Point: 445.621°C at 760 mmHg
• Flash Point: 223.304°C
• Appearance: /
• Density: 1.231g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: Bis(benzyloxycarbonyl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: Bis(benzyloxycarbonyl)amine(69032-13-9)
• EPA Substance Registry System: Bis(benzyloxycarbonyl)amine(69032-13-9)

Safety Data

• Hazardous Substances Data: 69032-13-9(Hazardous Substances Data)

Usage

General Description

Bis(benzyloxycarbonyl)amine is a chemical compound with the molecular formula (C7H7O2)2NH. It is a derivative of amine, containing two benzyloxycarbonyl (Cbz) groups attached to the nitrogen atom. Bis(benzyloxycarbonyl)amine is commonly used as a protecting group in organic synthesis to temporarily shield the amine functionality from unwanted reactions. The Cbz groups can be easily removed under mild conditions, revealing the free amine for further chemical manipulations. Bis(benzyloxycarbonyl)amine is an important reagent in the field of organic chemistry, providing a versatile strategy for the protection and deprotection of amine groups in various synthetic processes.

InChI:InChI=1/C16H15NO4/c18-15(20-11-13-7-3-1-4-8-13)17-16(19)21-12-14-9-5-2-6-10-14/h1-10H,11-12H2,(H,17,18,19)

Upstream product

• 69032-16-2 benzyloxycarbonyl isocyanate 
• 100-51-6 benzyl alcohol 
• 621-84-1 O-benzyl carbamate 
• 501-53-1 benzyl chloroformate 
• 97411-44-4 N,N-Dibenzyloxycarbonylhydrazine 
• 110-83-8 cyclohexene 
• 624-49-7 dimethylfumarate 
• 920-37-6 2-Chloroacrylonitrile 
• 292638-85-8 acrylic acid methyl ester 
• 624-48-6 dimethyl cis-but-2-ene-1,4-dioate 
• 156-60-5 trans-1,2-dichloroethylene 
• 100-42-5 styrene 
• 156-59-2 cis-1,2-Dichloroethylene 
• 57-13-6 urea 

Downstream Products

• 1001416-59-6 dibenzyl (1S,4R)-4-(2,6-dichloro-9H-purin-9-yl)cyclopent-2-enyliminodicarbonate 
• 952117-44-1 C₂₄H₂₈N₂O₄ 
• 952117-41-8 C₂₇H₂₈N₂O₄ 
• 1246449-89-7 9-bis(benzyloxycarbonyl)amino-2,3-dihydroxy-2,3-dimethyl-4-nonyne 
• 1246449-88-6 6-bis(benzyloxycarbonyl)amino-1-hexyne 
• 1161434-62-3 C₄₁H₅₅NO₇ 
• 810682-84-9 7-(iodopropyl)-N,N-dibenzyloxycarbonyl-1-(aminopropyl)-1,7-carborane 
• 136865-03-7 C₂₁H₂₃NO₆ 
• 425431-88-5 (3R,αS,1'S,α'R)-tert-butyl 3-(N-benzyloxycarbonyl-N-α-methylbenzylamino)-3-[4-(3'-iso-propoxy-3'-oxo-1'-(N-benzyl-N-α-methylbenzylamino)propyl)phenyl]propanoate 
• 132629-26-6 dibenzyl iminodicarboxylate potassium salt 
• 1026013-85-3 -3-amino>propyl>-L-leucyl>-N-methyl-L-phenylalaninamide 

Relevant articles and documents

Organic Compounds

A compound of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, and their preparation and use as pharmaceuticals wherein R1, R2 and R3 are as defined herein.

PURINE DERIVATIVES AS A2A AGONISTS

Compounds of formula (I):or stereoisomers or pharmaceutically acceptable salts thereof, wherein W, R1,R 2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by activatio

Synthetic Studies for Novel Structure of α-Nitrogenously Functionalized α-Fluorocarboxylic Acids. Part 1. The First Synthesis and Reactions of N-Protected α-Fluoroglycines

The first synthesis of the N-protected α-fluoro-α-amino acid esters 12, 13, 21 and 22, and the corresponding acids 16 and 24, is described.Reaction of ethyl and t-butyl bromofluoroacetates 4 and 9 with di-t-butyl and dibenzyl iminodicarboxylate potassium