69202-21-7

Basic information

• Product Name: 5-(4-METHOXYPHENYL)THIOPHENE-2-CARBOXYLICACIDMETHYLESTER,96%
• Synonyms: AKJKPXPOZBDPGB-UHFFFAOYSA-N
• CAS NO: 69202-21-7
• Molecular Formula: C₁₃H₁₂O₃S
• Molecular Weight: 248.3
• Mol File: 69202-21-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(4-METHOXYPHENYL)THIOPHENE-2-CARBOXYLICACIDMETHYLESTER,96%(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-METHOXYPHENYL)THIOPHENE-2-CARBOXYLICACIDMETHYLESTER,96%(69202-21-7)
• EPA Substance Registry System: 5-(4-METHOXYPHENYL)THIOPHENE-2-CARBOXYLICACIDMETHYLESTER,96%(69202-21-7)

Safety Data

• Hazardous Substances Data: 69202-21-7(Hazardous Substances Data)

Upstream product

• 14063-79-7 (Z)-3-chloro-3-(4-methoxyphenyl)acrylaldehyde 
• 2365-48-2 Methyl thioglycolate 
• 42545-43-7 2-(4-methoxyphenyl)thiophene 
• 124-38-9 carbon dioxide 
• 74-88-4 methyl iodide 
• 62224-19-5 5-bromo-2-thiophenecarboxylic acid methyl ester 
• 5720-07-0 4-methoxyphenylboronic acid 
• 7311-63-9 5-bromothiophene-2-carboxylic acid 
• 14063-79-7 3-chloro-3-(4-methoxyphenyl)acrylaldehyde 
• 124-41-4 sodium methylate 
• 623-51-8 ethyl 2-sulfanylacetate 

Downstream Products

• 116016-56-9 5-(4-methoxyphenyl)thiophene-2-carboxylic acid 
• 69202-24-0 5-(4-methoxy-phenyl)-thiophene-2-carboxylic acid hydrazide 

Relevant articles and documents

Direct Carboxylation of Electron-Rich Heteroarenes Promoted by LiO-tBu with CsF and [18]Crown-6

We herein demonstrate that the combination of LiO-tBu, CsF, and [18]crown-6 efficiently promotes the direct C?H carboxylation of electron-rich heteroarenes (benzothiophene, thiophene, benzofuran, and furan derivatives). A variety of functional groups, including methyl, methoxy, halo, cyano, amide, and keto moieties, are compatible with this system. The reaction proceeds via the formation of a tert-butyl carbonate species.

Microwave assisted synthesis of 5-arylthiophene-2-carboxylates

A simple and rapid method for the synthesis of 5-Aryl-thiophene-2- carboxylates 3 has been developed by the condensation of β-chlorovinyl aldehydes 1 with mercaptoacetic acid esters 2 under microwave irradiation conditions.