69287-12-3

Basic information

• Product Name: 1-Pentanone, 5-bromo-1-(4-methoxyphenyl)-
• CAS NO: 69287-12-3
• Molecular Formula: C12H15BrO2
• Molecular Weight: 271.154
• Mol File: 69287-12-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-Pentanone, 5-bromo-1-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pentanone, 5-bromo-1-(4-methoxyphenyl)-(69287-12-3)
• EPA Substance Registry System: 1-Pentanone, 5-bromo-1-(4-methoxyphenyl)-(69287-12-3)

Safety Data

• Hazardous Substances Data: 69287-12-3(Hazardous Substances Data)

Upstream product

• 110-52-1 1,4-dibromo-butane 
• 61885-75-4 (E)-4-methoxy-S-oxo-Sλ⁴-dithiobenzoic acid S'-p-tolyl ester 
• 2067-33-6 5-bromopentanoic acid 
• 154477-03-9 5-(4'-methoxyphenyl)-4-pentyn-1-ol 
• 120-92-3 cyclopentanone 
• 78195-96-7 1-(4-methoxyphenyl)cyclopentan-1-ol 
• 4509-90-4 5-bromovaleroyl chloride 
• 100-66-3 methoxybenzene 

Downstream Products

• 1567374-18-8 dimethyl 2-(4-methoxybenzoyl)cyclopentane-1,1-dicarboxylate 
• 1567374-03-1 C₁₇H₂₂O₆ 
• 282116-41-0 3,4,5,6-tetrahydro-2-(4-methoxyphenyl)-2H-thiopyran 
• 1467720-37-1 C₁₄H₂₀O₂S 
• 1467720-31-5 C₁₂H₁₈O₂S 
• 1467720-25-7 C₁₂H₁₇BrO₂ 
• 1467720-11-1 1-(4-methoxyphenyl)-5-(vinylsulfinyl)pentan-1-one 

Relevant articles and documents

Addition of benzyl ethers to alkynes: A metal-free synthesis of 1: H -isochromenes

Bromotrimethylsilane (TMSBr)-promoted intramolecular cyclization of (o-arylethynyl)benzyl ethers to form 1H-isochromenes at room temperature is reported. Further studies indicated that vinyl carbocations are the reaction intermediates which are stabilized by the conjugated aryl groups. Thus, O-addition of benzyl ethers/tetrahydropyrans to alkynes was achieved under metal-free, acidic conditions. These reaction conditions were compatible with an alkynyl Prins reaction; therefore, 1H-isochromenes were produced directly from alkynyl benzaldehydes and alkynyl alcohols using a one-pot procedure. This journal is

Catalytic Ring-Opening of Cyclic Alcohols Enabled by PCET Activation of Strong O-H Bonds

We report a new photocatalytic protocol for the redox-neutral isomerization of cyclic alcohols to linear ketones via C-C bond scission. Mechanistic studies demonstrate that key alkoxy radical intermediates in this reaction are generated via the direct homolytic activation of alcohol O-H bonds in an unusual intramolecular PCET process, wherein the electron travels to a proximal radical cation in concert with proton transfer to a weak Br?nsted base. Effective bond strength considerations are shown to accurately forecast the feasibility of alkoxy radical generation with a given oxidant/base pair.

Anodic cyclization of dimethyl 2-(5-aryl-5-oxopentyl)malonates into the corresponding dimethyl 2-aroylcyclopentane-1,1-dicarboxylates

A wide range of dimethyl 2-(5-aryl-5-oxopentyl)malonates was electrooxidized in methanol, in the presence of catalytic amount of potassium iodide, to give the corresponding dimethyl 2-aroylcyclopentane-1,1- dicarboxylates in high yields. The reactions were carried out under extremely mild reaction conditions, in which the optimal amount of electrolytic current ranged from 2.24 to 2.35 Fmol-1. The reaction presumably proceeded via a two-electron oxidation process, in which iodide ions played an important role as the electron carrier between the anode and the substrate.