69377-81-7

Basic information

• Product Name: Fluroxypyr
• Synonyms: ((4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy)-aceticaci;4-amino-3,5-dichloro-6-fluoro-2-pyridyloxyaceticacid;ff4014;[(4-Amino-3,5-dichloro-6-fluoropyridin-2-yl)oxy]acetic acid;2-[(4-AMino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy]acetic Acid;2-((4-Amino-3,5-dichloro-6-fluoropyridin-2-yl)oxy)acetic acid;ADVANCE;((4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy)acetic acid
• CAS NO: 69377-81-7
• Molecular Formula: C₇H₅Cl₂FN₂O₃
• Molecular Weight: 255.03
• Product Categories: Alpha sort;E-GAlphabetic;F;FA - FLPesticides&Metabolites;Herbicides;Pesticides&Metabolites;Pyridine
• Mol File: 69377-81-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 57.5°C
• Boiling Point: 399.4 °C at 760 mmHg
• Flash Point: 195.3 °C
• Appearance: white powder with the smell of soap
• Density: 1.3
• Vapor Pressure: 4.27E-07mmHg at 25°C
• Refractive Index: 1.608
• Storage Temp.: 0-6°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 2.22±0.10(Predicted)
• Merck: 13,4229
• BRN: 7136185
• CAS DataBase Reference: Fluroxypyr(CAS DataBase Reference)
• NIST Chemistry Reference: Fluroxypyr(69377-81-7)
• EPA Substance Registry System: Fluroxypyr(69377-81-7)

Safety Data

• Statements: 52/53
• Safety Statements: 61
• RIDADR: UN3077(solid)
• WGK Germany: 2
• RTECS: AF2500000
• Hazardous Substances Data: 69377-81-7(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 69377-81-7 differently. You can refer to the following data:
1. Fluroxypyr is a systemic and selective herbicide. Fluroxypyr is used for the control of broad-leaved weeds in small grain cereals, maize, pastures, range land and turf. Fluroxypyr is a synthetic auxin .
2. Fluroxypyr is a systemic and selective herbicide. Fluroxypyr is used for the control of broad-leaved weeds in small grain cereals, maize, pastures, range land and turf. Fluroxypyr is a synthetic auxin.

Definition

ChEBI: An aminopyridine that is pyridin-4-amine substituted by chloro groups at positions 3 and 5, a fluoro group at position 6 and a carboxymethoxy group at position 2.

Trade name

methyl ester: AGROSTAR; BOFIX FFC?; CABADEX?; CASCADE?; DOWCO? 433 MHE; FOREFRONT?; GALAXY GL184?; PARADIGM?; PASTUREGARD?; STARANE?; TOMAHAWK?; VISTA?; WIDEMATCH?, (fluroxypyr + clopyralid); XRM-5084?

Potential Exposure

Those who manufacture, distribute or use this pyridinecarboxylic acid/pyridine herbicide.

Environmental Fate

The DT50 in soil is relatively short, ranging from 5 to 9 days in experiments conducted in the laboratory. This rapid degradation is due to microbes.Because of its rapid soil degradation, little fluroxypyr is available for other dissipation processes, e.g., leaching.

Metabolism

Fluroxypyr is stable under acidic conditions and moderately stable in alkaline conditions; e.g., the DT50 in water at pH 9 is 185 days. Degradation occurs at temperatures above its melting point. Fluroxypyr is stable in light. Plant. The metabolism of fluroxypyr has not been fully described. Conjugates of fluroxypyr have been observed in tolerant plants. Soil. Fluroxypyr is rapidly metabolized by soil microbes via the removal of the carboxyl group or acetic acid group, yielding 4-amino-3,5-dichloro-6-fluoro- 2-methoxypyridine, and 4-amino-3,5-dichloro-6-fluoro-2- pyridinol, respectively.

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz ardous material, Technical Name Required.

Toxicity evaluation

Mammalian Toxicity. Fluroxypyr appears to be rapidly excreted, unmodified, in the urine of animals. The acute oral LD50 for rat is 2405 mg/kg. Weed Resistance/Modified Crop Tolerance. Fuerst et al. (48) reported fluroxypyr resistance in yellow starthistle (Centaurea solstitialis). No crops with modified tolerance toward fluroxypyr are currently in production.

Incompatibilities

May not be compatible with nitrates. Moisture may cause hydrolysis or other forms of decompo sition; forming a strong acid. Temperatures above 250℃ can cause decomposition. Methyl ester: Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is suffi ciently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solu tions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Waste Disposal

Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an after burner and scrubber. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesti cide containers.

InChI:InChI=1/C7H5Cl2FN2O3/c8-3-5(11)4(9)7(12-6(3)10)15-1-2(13)14/h1H2,(H2,11,12)(H,13,14)

Upstream product

• 2176-62-7 2,3,4,5,6-pentachloropyridine 
• 1737-93-5 3,5-dichloro-2,4,6-trifluoropyridine 
• 2840-00-8 4-amino-3,5-dichloro-2,6-difluoropyridine 

Relevant articles and documents

Method for preparing fluroxypyr

The invention discloses a method for preparing fluroxypyr, and belongs to the technical field of fine chemical engineering. The method comprises the steps of carrying out fluorination, carrying out amination, carrying out hydroxylation, carrying out stock solution extraction, carrying out condensation, carrying out hydrolysis and carrying out byproduct conversion. Byproducts and unreacted raw materials in a reaction process are used again through the steps of carrying out stock solution extraction and carrying out byproduct conversion, so that the utilization ratio of the raw materials is increased, the production cost and environmental treatment cost are reduced, and thus the method is applicable to large-scale production.

Soluble polymer based matrix for chemically active water insoluble components

This invention relates to a water soluble matrix composition comprising an anionic surfactant, a C6 to C18 alkyl pyrrolidone, urea and a water insoluble copolymer of vinyl pyrrolidone with not more than 50 wt. % of a comonomer selected from the group of an α-olefin, vinyl acetate, an acrylic or methacrylic acid ester and methacrylamide as a free flowing particulate solid which matrix is suitably mixed with a water insoluble, chemically active component, such as an agrochemical, to provide a clear sprayable film forming emulsion, such as a non-leachable film on a plant or other substrate surface. The invention also relates to the method of preparing the matrix and to the incorporation of an agrochemical concentrate and plant spray composition.

Stabilized agchemical concentrate and use thereof

The present invention relates to the stabilization of an agricultural chemical concentrate in aqueous solution and the stabilized concentrate which comprises: (a) between about 0.1 and about 20 wt. % of a stabilizer composition comprising: (1) between about 10 and about 90 wt. % of a water-insoluble, non-crosslinked, film forming polymer, and (2) a polymer solubilizing amount of an aromatic petroleum distillate or an oxygen-containing solvent of an N-alkyl pyrrolidone, a C3 to C8 alkanol, a dibasic acid lower alkyl ester, an ether having a boiling point above 150° C. or mixtures thereof and (b) between about 80 and about 99.9 wt. % concentrate containing a water-insoluble active agricultural chemical, a solvent for said agricultural chemical and a surfactant for said concentrate. The invention also relates to the use of said stabilized concentrate.