6970-25-8Relevant articles and documents
Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data
Aryal, Uma K.,Bailey, Barbara J.,Bum-Erdene, Khuchtumur,Corson, Timothy W.,Fishel, Melissa L.,Lee, Jonathan A.,Liu, Sheng,Meroueh, Samy O.,Pollok, Karen E.,Sishtla, Kamakshi,Wan, Jun,Wells, Clark D.,Xu, David,Zhou, Donghui
, p. 1424 - 1444 (2020/07/15)
Like most solid tumors, glioblastoma multiforme (GBM) harbors multiple overexpressed and mutated genes that affect several signaling pathways. Suppressing tumor growth of solid tumors like GBM without toxicity may be achieved by small molecules that selec