698392-52-8Relevant articles and documents
A practical synthesis of 2-aryl-indole-6-carboxylic acids
Gallou, Fabrice,Yee, Nathan,Qiu, Fenghe,Senanayake, Chris,Linz, Guenter,Schnaubelt, Juergen,Soyka, Rainer
, p. 883 - 885 (2007/10/03)
A practical synthesis of 2-aryl-indole-6-carboxylic acids was developed via a sequence consisting of SNAr reaction, reductive cyclization, hydrolysis and decarboxylation. This process is efficient in terms of operational simplicity, cost effectiveness and is amenable to large scale production.